Invitrogen™ DOK7 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA5101181

Catalog No. PIPA5101181

Description

Antibody detects endogenous levels of total DOK7.

The protein encoded by this gene is essential for neuromuscular synaptogenesis. The protein functions in aneural activation of muscle-specific receptor kinase, which is required for postsynaptic differentiation, and in the subsequent clustering of the acetylcholine receptor in myotubes. This protein can also induce autophosphorylation of muscle-specific receptor kinase. Mutations in this gene are a cause of familial limb-girdle myasthenia autosomal recessive, which is also known as congenital myasthenic syndrome type 1B. Alternative splicing results in multiple transcript variants.

Specifications

• Antigen: DOK7
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: DOK7
• Gene Alias: A930013K19Rik; AW049091; C4orf25; CMS10; CMS1B; docking protein 7; DOK7; Dok-7; Downstream of tyrosine kinase 7; EF-12; Oit5; oncoprotein induced transcript 5; protein Dok-7; RGD1566416
• Host Species: Rabbit
• Purification Method: Affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 231134, 285489
• Content And Storage: -20°C
• Form: Liquid

• Applications: Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
• Concentration: 1 mg/mL
• Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
• Gene Accession No.: Q18PE0, Q18PE1
• Gene Symbols: DOK7
• Immunogen: A synthesized peptide derived from human DOK7(Accession Q18PE1), corresponding to amino acid residues P415-T465.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse
• Product Type: Antibody
• Isotype: IgG

Safety and Handling

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