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Invitrogen™ DOPA Decarboxylase Monoclonal Antibody (CL2962)
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Catalog No. PIMA531379
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100 μL
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Catalog No. Quantity
PIMA531379 100 μL
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Catalog No. PIMA531379 Supplier Invitrogen™ Supplier No. MA531379
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Description

Mouse Monoclonal Antibody

Immunogen sequence: LETVMMDWLG KMLELPKAFL NEKAGEGGGV IQGSASEATL VALLAARTKV IHRLQAASPE LTQAAIMEKL VAYSSDQAHS SVERAGLIGG VKLKAIPSDG NFAMRASA Highest antigen sequence indentity to the following orthologs: Rat - 88%, Mouse - 90%.

DOPA Decarboxylase (aromatic L-amino acid decarboxylase, AADC; DDC) catalyzes the second reaction in the biosynthesis of catecholamines and serotonin (Waymire and Haycock, 2002; Berry et al., 1996; Haycock et al., 2003). It is also involved in the biosynthesis of trace amines. DDC antibodies can therefore be used as markers for dopaminergic, noradrenergic and serotonergic neurons in a variety of applications including depression, schizophrenia, Parkinson's disease and drug abuse (Kish et al., 2001; Zhu et al., 2000; Zhu et al., 1999).
TRUSTED_SUSTAINABILITY

Specifications

Antigen DOPA Decarboxylase
Applications Immunohistochemistry (Paraffin), Western Blot
Classification Monoclonal
Clone CL2962
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
Gene DDC
Gene Accession No. O88533, P14173, P20711
Gene Alias AADC; aromatic L-amino acid decarboxylase; aromatic-L-amino acid decarboxylase; aromatic-L-amino-acid decarboxylase; DDC; DOPA decarboxylase; dopa decarboxylase (aromatic L-amino acid decarboxylase); HGNC:2719; L-Dopa decarboxylase
Gene Symbols DDC
Host Species Mouse
Immunogen Recombinant protein fragment of Human DDC (Product #RP-90666)
Purification Method Protein A
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 13195, 1644, 24311
Target Species Human, Mouse, Rat
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG1
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