Invitrogen™ DOPA Decarboxylase Monoclonal Antibody (CL2962)

Mouse Monoclonal Antibody

Supplier:  Invitrogen™ MA531379

Catalog No. PIMA531379

Description

Immunogen sequence: LETVMMDWLG KMLELPKAFL NEKAGEGGGV IQGSASEATL VALLAARTKV IHRLQAASPE LTQAAIMEKL VAYSSDQAHS SVERAGLIGG VKLKAIPSDG NFAMRASA.

DOPA Decarboxylase (aromatic L-amino acid decarboxylase, AADC; DDC) catalyzes the second reaction in the biosynthesis of catecholamines and serotonin (Waymire and Haycock, 2002; Berry et al., 1996; Haycock et al., 2003). It is also involved in the biosynthesis of trace amines. DDC antibodies can therefore be used as markers for dopaminergic, noradrenergic and serotonergic neurons in a variety of applications including depression, schizophrenia, Parkinson's disease and drug abuse (Kish et al., 2001; Zhu et al., 2000; Zhu et al., 1999).

Specifications

• Antigen: DOPA Decarboxylase
• Classification: Monoclonal
• Concentration: 1 mg/mL
• Formulation: PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
• Gene Accession No.: O88533, P14173, P20711
• Gene Symbols: DDC
• Immunogen: Recombinant protein corresponding to Human DDC.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Rat
• Product Type: Antibody
• Isotype: IgG1

• Applications: Immunohistochemistry (Paraffin), Western Blot
• Clone: CL2962
• Conjugate: Unconjugated
• Gene: DDC
• Gene Alias: AADC; aromatic L-amino acid decarboxylase; aromatic-L-amino acid decarboxylase; aromatic-L-amino-acid decarboxylase; DDC; DOPA decarboxylase; dopa decarboxylase (aromatic L-amino acid decarboxylase); HGNC:2719; L-Dopa decarboxylase
• Host Species: Mouse
• Purification Method: Protein A
• Regulatory Status: RUO
• Gene ID (Entrez): 13195, 1644, 24311
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid