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Invitrogen™ DOPA Decarboxylase Polyclonal Antibody
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Catalog No. PIPA582597
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100 μL
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PIPA582597 100 μL
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Catalog No. PIPA582597 Supplier Invitrogen™ Supplier No. PA582597
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Description

Rabbit Polyclonal Antibody

Immunogen sequence: LETVMMDWLG KMLELPKAFL NEKAGEGGGV IQGSASEATL VALLAARTKV IHRLQAASPE LTQAAIMEKL VAYSSDQAHS SVERAGLIGG VKLKAIPSDG NFAMRASA Highest antigen sequence indentity to the following orthologs: Mouse - 90%, Rat - 88%.

DOPA Decarboxylase (aromatic L-amino acid decarboxylase, AADC; DDC) catalyzes the second reaction in the biosynthesis of catecholamines and serotonin (Waymire and Haycock, 2002; Berry et al., 1996; Haycock et al., 2003). It is also involved in the biosynthesis of trace amines. DDC antibodies can therefore be used as markers for dopaminergic, noradrenergic and serotonergic neurons in a variety of applications including depression, schizophrenia, Parkinson's disease and drug abuse (Kish et al., 2001; Zhu et al., 2000; Zhu et al., 1999).
TRUSTED_SUSTAINABILITY

Specifications

Antigen DOPA Decarboxylase
Applications Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
Classification Polyclonal
Concentration 0.05 mg/mL
Conjugate Unconjugated
Formulation PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
Gene DDC
Gene Accession No. P20711
Gene Alias AADC; aromatic L-amino acid decarboxylase; aromatic-L-amino acid decarboxylase; aromatic-L-amino-acid decarboxylase; DDC; DOPA decarboxylase; dopa decarboxylase (aromatic L-amino acid decarboxylase); HGNC:2719; L-Dopa decarboxylase
Gene Symbols DDC
Host Species Rabbit
Immunogen Recombinant protein corresponding to Human DDC. Recombinant protein control fragment (Product #RP-90666).
Purification Method Antigen affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 1644
Target Species Human
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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Safety and Handling

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