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Invitrogen™ Doublecortin Polyclonal Antibody
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Catalog No. PIPA5117905
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100 μL
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PIPA5117905 100 μL
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Catalog No. PIPA5117905 Supplier Invitrogen™ Supplier No. PA5117905
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Description

Rabbit Polyclonal Antibody

Doublecortin Polyclonal Antibody for Western Blot, IP

In the developing cortex, cortical neurons must migrate over long distances to reach the site of their final differentiation. DCX is a cytoplasmic protein which appears to direct neuronal migration by regulating the organization and stability of microtubules. It contains two doublecortin domains, which bind microtubules. In addition, this protein interacts with LIS1, the regulatory gamma subunit of platelet activating factor acetylhydrolase, and this interaction is important to proper microtubule function in the developing cortex. Mutations in the gene encoding DCX are a cause of X-linked lissencephaly.
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Specifications

Antigen Doublecortin
Applications Immunoprecipitation, Western Blot
Classification Polyclonal
Conjugate Unconjugated
Formulation PBS with no preservative
Gene DCX
Gene Accession No. O43602
Gene Alias DBCN; Dbct; DC; Dcn; DCX; doublecortex; doublecortin; doublin; lissencephalin-X; lissencephaly, X-linked (doublecortin); LISX; Lis-X; LIS-XD; Neuronal migration protein doublecortin; OTTHUMP00000023860; OTTHUMP00000216316; SCLH; XLIS
Gene Symbols DCX
Host Species Rabbit
Immunogen A synthetic peptide corresponding to the N-terminus of the Human DCX.
Purification Method Antigen affinity chromatography, Protein A
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 1641
Target Species Human
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Liquid
Isotype IgG
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