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Doublecortin Polyclonal Antibody, Rockland™
SDP

Goat Polyclonal Antibody

$174.73 - $636.24

Specifications

Antigen Doublecortin
Concentration 0.79 mg/mL
Applications ELISA, Immunofluorescence, Immunohistochemistry, Western Blot
Classification Polyclonal
Conjugate Unconjugated
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Products 2
Catalog Number Mfr. No. Quantity Price Quantity & Availability  
Catalog Number Mfr. No. Quantity Price Quantity & Availability  
50-199-1582
SDP
Encompass_Preferred
View Documents
Rockland Immunochemicals
600101MH8S
25 μg
Each for $174.73
Only null left
Add to Cart
 
50-199-1581
SDP
Encompass_Preferred
View Documents
Rockland Immunochemicals
600101MH8
100 μg
Each for $636.24
Only null left
Add to Cart
 
Description

Description

Store vial at -20°C prior to opening. Aliquot contents and freeze at -20°C or below for extended storage. Avoid cycles of freezing and thawing. Centrifuge product if not completely clear after standing at room temperature. This product is stable for several weeks at 4°C as an undiluted liquid. Dilute only prior to immediate use. This affinity purified antibody is directed against human Neuronal migration protein doublecortin. Blast analysis the immunogen sequence shows 100% identity withrat.

In the developing cortex, cortical neurons must migrate over long distances to reach the site of their final differentiation. DCX is a cytoplasmic protein which appears to direct neuronal migration by regulating the organization and stability of microtubules. It contains two doublecortin domains, which bind microtubules. In addition, this protein interacts with LIS1, the regulatory gamma subunit of platelet activating factor acetylhydrolase, and this interaction is important to proper microtubule function in the developing cortex. Mutations in the gene encoding DCX are a cause of X-linked lissencephaly.
Specifications

Specifications

Doublecortin
ELISA, Immunofluorescence, Immunohistochemistry, Western Blot
Unconjugated
Goat
Human, Mouse, Rat
O43602, O88809, Q9ESI7
13193, 1641, 84394
Primary
Antibody
0.79 mg/mL
Polyclonal
Liquid
RUO
0.02M potassium phosphate with 0.15M NaCl and 0.01% sodium azide; pH 7.2
BOS_25702; DBCN; Dbct; DC; Dcn; Dcx; doublecortex; doublecortin; Doublin; Lissencephalin-X; lissencephaly, X-linked (doublecortin); LISX; Lis-X; LIS-XD; Neuronal migration protein doublecortin; OTTHUMP00000023860; OTTHUMP00000216316; SCLH; XLIS
DCX
-20°C, Avoid Freeze/Thaw Cycles
DCX
Videos
SDS
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Documents

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