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Doxycycline hydrochloride Alfa Aesar™

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Quantity:
1g
5g
25g
10592-13-9
C22H25ClN2O8
480.898
MFCD03427564
PTNZGHXUZDHMIQ-CVHRZJFOSA-N
54706018
[(1S,4aR,11R,11aR,12S,12aR)-3-carbamoyl-4,4a,6,7,12-pentahydroxy-11-methyl-2,5-dioxo-11,11a,12,12a-tetrahydro-1H-tetracen-1-yl]-dimethylazanium;chloride
CC1C2C(C3C(C(=O)C(=C(C3(C(=O)C2=C(C4=C1C=CC=C4O)O)O)O)C(=O)N)[NH+](C)C)O.[Cl-]
10592-13-9
C22H25ClN2O8
480.898
MFCD03427564
PTNZGHXUZDHMIQ-CVHRZJFOSA-N
54706018
[(1S,4aR,11R,11aR,12S,12aR)-3-carbamoyl-4,4a,6,7,12-pentahydroxy-11-methyl-2,5-dioxo-11,11a,12,12a-tetrahydro-1H-tetracen-1-yl]-dimethylazanium;chloride
CC1C2C(C3C(C(=O)C(=C(C3(C(=O)C2=C(C4=C1C=CC=C4O)O)O)O)C(=O)N)[NH+](C)C)O.[Cl-]

Inhibits angiogenesis and reduces lung metastases by inhibiting matrix metalloproteinases

Applications
Inhibits angiogenesis and reduces lung metastases by inhibiting matrix metalloproteinases.Doxycycline hydrochloride is an antibiotic used to inhibit matrix metalloproteinases like type 1 collagenase in studies on would healing and tissue remodeling. It shows the broad spectrum antibacterial and antiprotozoan activity. It is often used to treat lyme disease, chronic prostatitis, sinusitis, pelvic inflammatory disease acne, rosacea, and rickettsial infections and prophylaxis of anthrax.

Solubility
Soluble in water to 50mg/ml. May require warming.

Notes
Research Use only: Not intended for animal or human diagnostic or therapeutic use.Incompatible with strong oxidizing agents.
Solubility Information Soluble in water to 50mg/ml; May require warming
Formula Weight 480.9
Physical Form Crystalline Powder
Color Yellow
Melting Point 195°C to 201°C
Quantity 5g
Chemical Name or Material Doxycycline hydrochloride

GHS H Statement
H302-H315-H319-H335
Harmful if swallowed.
Causes skin irritation.
Causes serious eye irritation.
May cause respiratory irritation.

GHS P Statement
P261-P280-P305+P351+P338-P304+P340-P405-P501a
Avoid breathing dust/fume/gas/mist/vapors/spray.
Wear protective gloves/protective clothing/eye protection/face protection.
IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
IF INHALED: Remove to fresh air and keep at rest in a position comfortable for breathing.
Store locked up.
Dispose of contents/container in accordance with local/regional/national/international regulations.

Warning