Invitrogen™ DPCR1 Monoclonal Antibody (213201)

Mouse Monoclonal Antibody

Supplier:  Invitrogen™ MA523934

Catalog No. PIMA523934

Description

This antibody stains human DPCR-1-transfected cells but not irrelevant transfectants. Reconstitute at 0.5 mg/mL in sterile PBS. Endoxin level is <0.10 EU per 1 μg of the antibody by the LAL method.

The DPCR1 gene, known as diffuse panbronchiolitis critical region 1, encodes a protein involved in immune responses and epithelial cell function, particularly in the respiratory system. Although the specific functions of DPCR1 are not extensively characterized, the gene is located within a region linked to diffuse panbronchiolitis, a chronic inflammatory lung disease. DPCR1 is thought to contribute to immune regulation, potentially influencing innate immune responses and epithelial cell interactions critical for maintaining respiratory health. Its expression in airway epithelial cells suggests a role in modulating mucus production, barrier integrity, and protection against pathogens. Aberrant expression of DPCR1 may impact respiratory function, contributing to conditions such as asthma or chronic obstructive pulmonary disease (COPD) by affecting immune responses and inflammation. Understanding DPCR1's functions and regulatory mechanisms in the respiratory system is essential for exploring its potential as a therapeutic target for respiratory diseases characterized by chronic inflammation and immune dysregulation.

Specifications

• Antigen: DPCR1
• Classification: Monoclonal
• Concentration: 0.5 mg/mL
• Formulation: PBS with 5% trehalose and No Preservative
• Gene Accession No.: Q3MIW9
• Gene Symbols: DPCR1
• Immunogen: NS0 mouse myeloma cell line transfected with human DPCR-1 Met1-Arg235.
• Quantity: 100 μg
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG2a

• Applications: Flow Cytometry
• Clone: 213201
• Conjugate: Unconjugated
• Gene: DPCR1
• Gene Alias: bCX105N19.6; C6orf37; diffuse panbronchiolitis critical region 1; diffuse panbronchiolitis critical region protein 1; DPCR1; MGC126710; MGC126712; Mucin-like protein 3; MUCL3; PBLT
• Host Species: Mouse
• Purification Method: Protein A/G
• Regulatory Status: RUO
• Gene ID (Entrez): 135656
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Form: Lyophilized