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Invitrogen™ DPCR1 Monoclonal Antibody (213201)
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Catalog No. PIMA523934
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100 μg
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Catalog No. Quantity
PIMA523934 100 μg
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Catalog No. PIMA523934 Supplier Invitrogen™ Supplier No. MA523934
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Description

Mouse Monoclonal Antibody

This antibody stains human DPCR-1-transfected cells but not irrelevant transfectants. Reconstitute at 0.5 mg/mL in sterile PBS. Endoxin level is <0.10 EU per 1 μg of the antibody by the LAL method.

The DPCR1 gene, known as diffuse panbronchiolitis critical region 1, encodes a protein involved in immune responses and epithelial cell function, particularly in the respiratory system. Although the specific functions of DPCR1 are not extensively characterized, the gene is located within a region linked to diffuse panbronchiolitis, a chronic inflammatory lung disease. DPCR1 is thought to contribute to immune regulation, potentially influencing innate immune responses and epithelial cell interactions critical for maintaining respiratory health. Its expression in airway epithelial cells suggests a role in modulating mucus production, barrier integrity, and protection against pathogens. Aberrant expression of DPCR1 may impact respiratory function, contributing to conditions such as asthma or chronic obstructive pulmonary disease (COPD) by affecting immune responses and inflammation. Understanding DPCR1's functions and regulatory mechanisms in the respiratory system is essential for exploring its potential as a therapeutic target for respiratory diseases characterized by chronic inflammation and immune dysregulation.
TRUSTED_SUSTAINABILITY

Specifications

Antigen DPCR1
Applications Flow Cytometry
Classification Monoclonal
Clone 213201
Concentration 0.5 mg/mL
Conjugate Unconjugated
Formulation PBS with 5% trehalose and No Preservative
Gene DPCR1
Gene Accession No. Q3MIW9
Gene Alias bCX105N19.6; C6orf37; diffuse panbronchiolitis critical region 1; diffuse panbronchiolitis critical region protein 1; DPCR1; MGC126710; MGC126712; Mucin-like protein 3; MUCL3; PBLT
Gene Symbols DPCR1
Host Species Mouse
Immunogen NS0 mouse myeloma cell line transfected with human DPCR-1 Met1-Arg235.
Purification Method Protein A/G
Quantity 100 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 135656
Target Species Human
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Lyophilized
Isotype IgG2a
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