Invitrogen™ DPCR1 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA543536

Catalog No. PIPA543536

Description

Peptide sequence: SHLNKTEVTH QVPTGSFTLI TSRTKLSSIT SEATGNESHP YLNKDGSQKG Sequence homology: Human: 100%.

The DPCR1 gene, known as diffuse panbronchiolitis critical region 1, encodes a protein involved in immune responses and epithelial cell function, particularly in the respiratory system. Although the specific functions of DPCR1 are not extensively characterized, the gene is located within a region linked to diffuse panbronchiolitis, a chronic inflammatory lung disease. DPCR1 is thought to contribute to immune regulation, potentially influencing innate immune responses and epithelial cell interactions critical for maintaining respiratory health. Its expression in airway epithelial cells suggests a role in modulating mucus production, barrier integrity, and protection against pathogens. Aberrant expression of DPCR1 may impact respiratory function, contributing to conditions such as asthma or chronic obstructive pulmonary disease (COPD) by affecting immune responses and inflammation. Understanding DPCR1's functions and regulatory mechanisms in the respiratory system is essential for exploring its potential as a therapeutic target for respiratory diseases characterized by chronic inflammation and immune dysregulation.

Specifications

• Antigen: DPCR1
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: DPCR1
• Gene Alias: bCX105N19.6; C6orf37; diffuse panbronchiolitis critical region 1; diffuse panbronchiolitis critical region protein 1; DPCR1; MGC126710; MGC126712; Mucin-like protein 3; MUCL3; PBLT
• Host Species: Rabbit
• Purification Method: Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 135656
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Form: Liquid

• Applications: Western Blot
• Concentration: 0.5 mg/mL
• Formulation: PBS with 2% sucrose and 0.09% sodium azide
• Gene Accession No.: Q3MIW9
• Gene Symbols: DPCR1
• Immunogen: Synthetic peptide directed towards the C-terminal of human DPCR1 (aa 383-432).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG

Safety and Handling

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