Invitrogen™ DPH2 Monoclonal Antibody (3F7)

Mouse Monoclonal Antibody

Supplier:  Invitrogen™ MA518756

Catalog No. PIMA518756

Description

Peptide Sequence: MESMFSSPAE AALQRETGVP GLLTPLPDLD GVYELERVAG FVRDLGCERV ALQFPDQLLG DAVAVAARLE ETTGSKMFIL GDTAYGSCCV DVLGAEQAGA QALIHFGPAC LSPPARPLPV AFVLRQRSVA LELCVKAFEA QNPDPKAPVV LLSEPACAHA LEALATLLRP RYLDLLVSSP AFPQPVGSLS PEPMPLERFG RRFPLAPGRR LEEYGAFYVG GSKASPDPDL DPDLSRLLLG WAPGQPFSSC CPDTGKTQDE GARAGRLRAR RRYLVERARD ARVVGLLAGT LGVAQHREAL AHLRNLTQAA GKRSYVLALG RPTPAKLANF PEVDVFVLLA CPLGALAPQL SGSFFQPILA PCELEAACNP AWPPPGLAPH LTHYADLLPG SPFHVALPPP ESELWETPDV SLITGDLRPP PAWKSSNDHG SLALTPRPQL ELAESSPAAS FLSSRSWQGL EPRLGQTPVT EAVSGRRGIA IAYEDEGSG.

This gene is one of two human genes similar to the yeast gene dph2. The yeast gene was identified by its ability to complement a diphthamide mutant strain, and thus probably functions in diphthamide biosynthesis. Diphthamide is a post-translationally modified histidine residue present in elongation factor 2 (EF2) that is the target of diphtheria toxin ADP-ribosylation. Two transcript variants encoding different isoforms have been found for this gene.

Specifications

• Antigen: DPH2
• Classification: Monoclonal
• Concentration: 1 mg/mL
• Formulation: PBS with no preservative; pH 7.4
• Gene Accession No.: Q9BQC3
• Gene Symbols: DPH2
• Immunogen: DPH2 (AAH16956, 1 a.a. ~ 489 a.a) full-length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
• Quantity: 100 μg
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG2a κ

• Applications: ELISA, Western Blot, Immunocytochemistry
• Clone: 3F7
• Conjugate: Unconjugated
• Gene: DPH2
• Gene Alias: 2-(3-amino-3-carboxypropyl)histidine synthase subunit 2; 9130020C19Rik; AI467389; diphthamide biosynthesis 2; diphthamide biosynthesis protein 2; diphthamide biosynthesis protein 2 homolog-like 2; diphthamide biosynthesis-like protein 2; Diphtheria toxin resistance protein 2; diptheria toxin resistance protein required for diphthamide biosynthesis (Saccharomyces)-like 1; diptheria toxin resistance protein required for diphthamide biosynthesis (Saccharomyces)-like 2; diptheria toxin resistance protein required for diphthamide biosynthesis-like 2; DPH2; DPH2 homolog; DPH2 homolog (S. cerevisiae); DPH2L2; DPH2-like 2; EGK_00671; MmDph2; S-adenosyl-L-methionine:L-histidine 3-amino-3-carboxypropyltransferase 2; S-adenosyl-L-methionine:L-histidine 3-amino-3-carboxypropyltransferase DPH2
• Host Species: Mouse
• Purification Method: Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 1802
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Form: Liquid