Invitrogen™ DPM2 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA564178

Catalog No. PIPA564178

Description

Immunogen sequence: SSPPPLDPGQ GFGKTPPLNM LPHFGGAGSC LPRTHPWGFP VHPSRLPVSN LWVSWC Highest antigen sequence identity to the following orthologs: Mouse - 38%, Rat - 38%.

Dolichol-phosphate mannose (Dol-P-Man) serves as a donor of mannosyl residues on the lumenal side of the endoplasmic reticulum (ER). Lack of Dol-P-Man results in defective surface expression of GPI-anchored proteins. Dol-P-Man is synthesized from GDP-mannose and dolichol-phosphate on the cytosolic side of the ER by the enzyme dolichyl-phosphate mannosyltransferase. The protein encoded by this gene is a hydrophobic protein that contains 2 predicted transmembrane domains and a putative ER localization signal near the C terminus. This protein associates with DPM1 in vivo and is required for the ER localization and stable expression of DPM1 and also enhances the binding of dolichol-phosphate to DPM1.

Specifications

• Antigen: DPM2
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: DPM2
• Gene Alias: CDG1U; dolichol phosphate-mannose biosynthesis regulatory protein; Dolichol-phosphate mannose synthase subunit 2; dolichyl-phosphate mannosyltransferase polypeptide 2, regulatory subunit; DPM synthase complex subunit; DPM synthase subunit 2; DPM2; My026
• Host Species: Rabbit
• Purification Method: Antigen Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 8818
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Immunohistochemistry (Paraffin)
• Concentration: 0.1 mg/mL
• Formulation: PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
• Gene Accession No.: O94777
• Gene Symbols: DPM2
• Immunogen: Recombinant protein corresponding to Human DPM2. Recombinant protein control fragment (Product #RP-103567).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG