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Invitrogen™ DPM2 Polyclonal Antibody
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Catalog No. PIPA564178
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100 μL
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PIPA564178 100 μL
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Catalog No. PIPA564178 Supplier Invitrogen™ Supplier No. PA564178
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Description

Rabbit Polyclonal Antibody

Immunogen sequence: SSPPPLDPGQ GFGKTPPLNM LPHFGGAGSC LPRTHPWGFP VHPSRLPVSN LWVSWC Highest antigen sequence identity to the following orthologs: Mouse - 38%, Rat - 38%.

Dolichol-phosphate mannose (Dol-P-Man) serves as a donor of mannosyl residues on the lumenal side of the endoplasmic reticulum (ER). Lack of Dol-P-Man results in defective surface expression of GPI-anchored proteins. Dol-P-Man is synthesized from GDP-mannose and dolichol-phosphate on the cytosolic side of the ER by the enzyme dolichyl-phosphate mannosyltransferase. The protein encoded by this gene is a hydrophobic protein that contains 2 predicted transmembrane domains and a putative ER localization signal near the C terminus. This protein associates with DPM1 in vivo and is required for the ER localization and stable expression of DPM1 and also enhances the binding of dolichol-phosphate to DPM1.
TRUSTED_SUSTAINABILITY

Specifications

Antigen DPM2
Applications Immunohistochemistry (Paraffin)
Classification Polyclonal
Concentration 0.1 mg/mL
Conjugate Unconjugated
Formulation PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
Gene DPM2
Gene Accession No. O94777
Gene Alias CDG1U; dolichol phosphate-mannose biosynthesis regulatory protein; Dolichol-phosphate mannose synthase subunit 2; dolichyl-phosphate mannosyltransferase polypeptide 2, regulatory subunit; DPM synthase complex subunit; DPM synthase subunit 2; DPM2; My026
Gene Symbols DPM2
Host Species Rabbit
Immunogen Recombinant protein corresponding to Human DPM2. Recombinant protein control fragment (Product #RP-103567).
Purification Method Antigen affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 8818
Target Species Human
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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