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Tocris Bioscience™ DPNB-ABT 594

Catalog No. 67065
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5 mg
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Catalog No. Quantity
67-065 5 mg
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Catalog No. 67-065 Supplier Tocris Bioscience™ Supplier No. 6706/5

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Description

Caged ABT 594 (Cat. No. 6576); suitable for one- or two-photon photolysis

DPNB-ABT 594 is a nitrobenzyl-caged ABT 594 (Cat. No. 6576), a selective α4β2 nAChR agonist. One-photon uncaging evokes large inward currents and Ca2+ transients on cell bodies and dendrites of medial habenular neurons in mouse brain slices. Two-photon uncaging induces fast nAChR-mediated currents. Photolyzed with high quantum yield of 0.20. Effective photolysis occurs using one- or two-photon excitation; one-photon uncaging requires illumination at 410 nm for 1.5-3 ms; two-photon uncaging requires illumination with appropriate two photon pulse laser at 710 nm for ∽2 ms.

Specifications

Chemical Name or Material 5-(((2 R)-1-(1-(4,5-Bis(2-(2-(2-methoxyethoxy)ethoxy)ethoxy)-2-nitrophenyl)ethyl)azetidin-2-yl)methoxy)-2-chloropyridine
Quantity 5 mg
Target Nicotinic (a4b2) Receptor Agonists
Molecular Formula C31H46ClN3O11
Formula Weight 672.16
Purity 98%
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