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  9. DPO-1, Tocris Bioscience™

DPO-1, Tocris Bioscience™

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Quantity:
10mg
50mg
This item is not returnable. View return policy
43077-30-1
C22H29OP
340.447
BPCNGVCAHAIZEE-COPCDDAFSA-N
dpo-1,neomenthyldiphenylphosphine oxide,+-neomenthyl diphenylphosphine oxide,1s,2s,5r-5-methyl-2-1-methylethyl cyclohexyl diphenyl-phosphine oxide,diphenyl phosphine oxide-1,dpo-1, needles nmr,1s,2s,5r-2-isopropyl-5-methylcyclohexyl diphenyl phosphine oxide,1s,2s,5r-2-isopropyl-5-methylcyclohexyl phenyl phosphoroso benzene,1s,2s,5r-5-methyl-2-propan-2-yl cyclohexyl oxo diphenyl-lambda~5~-phosphane,1s-1?,2?,5?-5-methyl-2-1-methylethyl cyclohexyl diphenylphosphine oxide
21678144
[[(1S,2S,5R)-5-methyl-2-propan-2-ylcyclohexyl]-phenylphosphoryl]benzene
CC1CCC(C(C1)P(=O)(C2=CC=CC=C2)C3=CC=CC=C3)C(C)C
This item is not returnable. View return policy
43077-30-1
C22H29OP
340.447
BPCNGVCAHAIZEE-COPCDDAFSA-N
dpo-1,neomenthyldiphenylphosphine oxide,+-neomenthyl diphenylphosphine oxide,1s,2s,5r-5-methyl-2-1-methylethyl cyclohexyl diphenyl-phosphine oxide,diphenyl phosphine oxide-1,dpo-1, needles nmr,1s,2s,5r-2-isopropyl-5-methylcyclohexyl diphenyl phosphine oxide,1s,2s,5r-2-isopropyl-5-methylcyclohexyl phenyl phosphoroso benzene,1s,2s,5r-5-methyl-2-propan-2-yl cyclohexyl oxo diphenyl-lambda~5~-phosphane,1s-1?,2?,5?-5-methyl-2-1-methylethyl cyclohexyl diphenylphosphine oxide
21678144
[[(1S,2S,5R)-5-methyl-2-propan-2-ylcyclohexyl]-phenylphosphoryl]benzene
CC1CCC(C(C1)P(=O)(C2=CC=CC=C2)C3=CC=CC=C3)C(C)C

Description

Blocker of KV1.5 channel and IKur current

Blocker of I Kur ultrarapid delayed rectifier potassium current and K V 1.5 channels (IC 50 = 0.31 μM for rK V 1.5). Displays selectivity for inhibition of I Kur over I to (8-fold), I K1 I Kr and I Ks (20-fold) in native myocytes and selectivity for rat recombinant K V 1.5 over K V 3.1 (∽ 15-fold). Increases action potential duration in atrial but not ventricular myocytes and prevents atrial arrhythmia.
Quantity 50mg
Formula Weight 340.44
Percent Purity >99%
Chemical Name or Material DPO-1

Safety and Handling

Recommended Storage : Store at +4°C