Invitrogen™ DPPA4 Polyclonal Antibody

Catalog No.	Quantity
PIPA547530	100 μg

Catalog No. PIPA547530 Supplier Invitrogen™ Supplier No. PA547530

Description

Goat Polyclonal Antibody

In direct ELISAs and Western blots, less than 5% cross-reactivity with recombinant human DPPA4 and recombinant mouse DPPA5 is observed. Reconstitute at 0.2 mg/mL in sterile PBS.

The DPPA4 gene encodes developmental pluripotency associated 4, a protein that plays a crucial role in maintaining stem cell pluripotency and facilitating early embryonic development. DPPA4 is primarily expressed in pluripotent stem cells, such as embryonic stem cells, where it contributes to the regulation of gene expression and chromatin structure necessary for pluripotency and differentiation. This protein is also involved in the establishment of epigenetic marks that influence developmental pathways, ensuring the proper formation of tissue types during embryogenesis. DPPA4 functions in stem cell renewal and differentiation, impacting cellular processes that are fundamental to early development. Beyond its roles in normal physiology, DPPA4 has been studied in the context of oncology, where its expression is often upregulated in certain cancers, indicating its potential as a biomarker for tumorigenic stem cell-like properties. Research continues to explore DPPA4's mechanisms and interactions to understand its contributions to development and its implications in disease states, particularly in cancer biology and regenerative medicine.

Specifications

• Antigen: DPPA4
• Applications: Western Blot, Immunocytochemistry
• Classification: Polyclonal
• Concentration: 0.2 mg/mL
• Conjugate: Unconjugated
• Formulation: PBS with 5% trehalose and No Preservative
• Gene: DPPA4
• Gene Accession No.: Q8CCG4
• Gene Alias: 2410091M23Rik; C76608; developmental pluripotency associated 4; developmental pluripotency-associated protein 4; Dppa4; ECAT15-1; Embryonic stem cell-associated transcript 15-1 protein; LOC685378; similar to developmental pluripotency associated 4 isoform 1
• Gene Symbols: DPPA4
• Host Species: Goat
• Immunogen: E. coli-derived recombinant mouse DPPA4 Asn125-Gly296.
• Purification Method: Antigen affinity chromatography
• Quantity: 100 μg
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Gene ID (Entrez): 73693
• Target Species: Mouse
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Product Type: Antibody
• Form: Lyophilized
• Isotype: IgG

Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov