Invitrogen™ DPPA4 Polyclonal Antibody

Catalog No.	Quantity
PIPA583266	100 μL

Catalog No. PIPA583266 Supplier Invitrogen™ Supplier No. PA583266

Description

Rabbit Polyclonal Antibody

Immunogen sequence: ASSTSMEKAK GKEWTSTEKS REEDQQASNQ PNSIALPGTS AKRTKEKMSI KGSKVLCPKK KAEHTDNPRP QKKIPIPPLP SKLPPVNLIH RD Highest antigen sequence indentity to the following orthologs: Mouse - 39%, Rat - 33%.

The DPPA4 gene encodes developmental pluripotency associated 4, a protein that plays a crucial role in maintaining stem cell pluripotency and facilitating early embryonic development. DPPA4 is primarily expressed in pluripotent stem cells, such as embryonic stem cells, where it contributes to the regulation of gene expression and chromatin structure necessary for pluripotency and differentiation. This protein is also involved in the establishment of epigenetic marks that influence developmental pathways, ensuring the proper formation of tissue types during embryogenesis. DPPA4 functions in stem cell renewal and differentiation, impacting cellular processes that are fundamental to early development. Beyond its roles in normal physiology, DPPA4 has been studied in the context of oncology, where its expression is often upregulated in certain cancers, indicating its potential as a biomarker for tumorigenic stem cell-like properties. Research continues to explore DPPA4's mechanisms and interactions to understand its contributions to development and its implications in disease states, particularly in cancer biology and regenerative medicine.

Specifications

• Antigen: DPPA4
• Applications: Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
• Classification: Polyclonal
• Concentration: 0.2 mg/mL
• Conjugate: Unconjugated
• Formulation: PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
• Gene: DPPA4
• Gene Accession No.: Q7L190
• Gene Alias: 2410091M23Rik; C76608; developmental pluripotency associated 4; developmental pluripotency-associated protein 4; Dppa4; ECAT15-1; Embryonic stem cell-associated transcript 15-1 protein; LOC685378; similar to developmental pluripotency associated 4 isoform 1
• Gene Symbols: DPPA4
• Host Species: Rabbit
• Immunogen: Recombinant protein corresponding to Human DPPA4. Recombinant protein control fragment (Product #RP-96328).
• Purification Method: Antigen affinity chromatography
• Quantity: 100 μL
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Gene ID (Entrez): 55211
• Target Species: Human
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Product Type: Antibody
• Form: Liquid
• Isotype: IgG