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  5. Tocris Bioscience™ DR 4485 Hydrochloride
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Tocris Bioscience™ DR 4485 Hydrochloride

High affinity and selective 5-HT7 antagonist; orally bioavailable

Supplier:  Tocris Bioscience™ 5005/10

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Catalog No. 50-051-0


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Description

Description

DR 4485 hydrochloride is a high affinity and selective 5-HT7 antagonist (pKi = 8.14). Exhibits selectivity for 5-HT7 over other 5-HT receptors. Inhibits 5-HT-induced cAMP accumulation in HEK-293 cells expressing the 5-HT7 receptor. Orally bioavailable.
Specifications

Specifications

6-Chloro-2a-[4-[4-(4-chlorophenyl)-3,6-dihydro-1(2H)-pyridinyl]butyl]-2a,3,4,5-tetrahydrobenz[cd]indol-2(1H)-one hydrochloride
10 mg
491.88
402942-53-4
C26H28Cl2N2O.HCl
98%
Safety and Handling

Safety and Handling

Recommended Storage : Desiccate at Room Temperature

SDS
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