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  5. Tocris Bioscience™ DR 4485 Hydrochloride

Tocris Bioscience™ DR 4485 Hydrochloride
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Catalog No. 500550RD
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Quantity:
10 mg
50 mg
This item is not returnable. View return policy
This item is not returnable. View return policy

Description

High affinity and selective 5-HT7 antagonist; orally bioavailable

DR 4485 hydrochloride is a high affinity and selective 5-HT7 antagonist (pKi = 8.14). Exhibits selectivity for 5-HT7 over other 5-HT receptors. Inhibits 5-HT-induced cAMP accumulation in HEK-293 cells expressing the 5-HT7 receptor. Orally bioavailable.

Specifications

Chemical Name or Material 6-Chloro-2a-[4-[4-(4-chlorophenyl)-3,6-dihydro-1(2H)-pyridinyl]butyl]-2a,3,4,5-tetrahydrobenz[cd]indol-2(1H)-one hydrochloride
CAS 402942-53-4
Quantity 50 mg
Molecular Formula C26H28Cl2N2O.HCl
Formula Weight 491.88
Purity 98%
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