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Invitrogen™ DR1 Polyclonal Antibody
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Catalog No. PIPA562242
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100 μL
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PIPA562242 100 μL
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Catalog No. PIPA562242 Supplier Invitrogen™ Supplier No. PA562242
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Description

Rabbit Polyclonal Antibody

Immunogen sequence: MASSSGNDDD LTIPRAAINK MIKETLPNVR VANDARELVV NCCTEFIHLI SSEANEICNK SEKKTISPEH VIQALESLGF G Highest antigen sequence identity to the following orthologs: Mouse - 100%, Rat - 100%.

This gene encodes a TBP- (TATA box-binding protein) associated phosphoprotein that represses both basal and activated levels of transcription. The encoded protein is phosphorylated in vivo and this phosphorylation affects its interaction with TBP. This protein contains a histone fold motif at the amino terminus, a TBP-binding domain, and a glutamine- and alanine-rich region. The binding of DR1 repressor complexes to TBP-promoter complexes may establish a mechanism in which an altered DNA conformation, together with the formation of higher order complexes, inhibits the assembly of the preinitiation complex and controls the rate of RNA polymerase II transcription.
TRUSTED_SUSTAINABILITY

Specifications

Antigen DR1
Applications Immunohistochemistry (Paraffin), Western Blot
Classification Polyclonal
Concentration 0.1 mg/mL
Conjugate Unconjugated
Formulation PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
Gene Dr1
Gene Accession No. Q01658
Gene Alias 1700121L09Rik; Down-regulator of transcription 1; down-regulator of transcription 1, TBP-binding (negative cofactor 2); Dr1; Dr1l; NC2; NC2B; NC2beta; NC2-beta; negative cofactor 2; negative cofactor 2 beta; negative cofactor 2-beta; Protein Dr1; similar to down-regulator of transcription 1; TATA-binding protein-associated phosphoprotein; wu:fj15f04; zgc:152914
Gene Symbols Dr1
Host Species Rabbit
Immunogen Recombinant protein corresponding to Human DR1. Recombinant protein control fragment (Product #RP-94124).
Purification Method Antigen affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 1810
Target Species Human
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov
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