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Invitrogen™ DR1 Polyclonal Antibody
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Catalog No. PIPA589144
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100 μL
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PIPA589144 100 μL
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Catalog No. PIPA589144 Supplier Invitrogen™ Supplier No. PA589144
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Description

Rabbit Polyclonal Antibody

Immunogen sequence: MASSSGNDDD LTIPRAAINK MIKETLPNVR VANDARELVV NCCTEFIHLI SSEANEICNK SEKKTISPEH VIQALESLGF GSYISEVKEV LQECKTVALK RRKASSRLEN LGIPEEELLR QQQELFAKAR QQQAELAQQE WLQMQQAAQQ AQLAAASASA SNQAGSSQDE EDDDDI; Positive Samples: Mouse spleen; Cellular Location: Nucleus.

This gene encodes a TBP- (TATA box-binding protein) associated phosphoprotein that represses both basal and activated levels of transcription. The encoded protein is phosphorylated in vivo and this phosphorylation affects its interaction with TBP. This protein contains a histone fold motif at the amino terminus, a TBP-binding domain, and a glutamine- and alanine-rich region. The binding of DR1 repressor complexes to TBP-promoter complexes may establish a mechanism in which an altered DNA conformation, together with the formation of higher order complexes, inhibits the assembly of the preinitiation complex and controls the rate of RNA polymerase II transcription.
TRUSTED_SUSTAINABILITY

Specifications

Antigen DR1
Applications ELISA, Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
Classification Polyclonal
Concentration 0.92 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
Gene Dr1
Gene Accession No. Q01658, Q91WV0
Gene Alias 1700121L09Rik; Down-regulator of transcription 1; down-regulator of transcription 1, TBP-binding (negative cofactor 2); Dr1; Dr1l; NC2; NC2B; NC2beta; NC2-beta; negative cofactor 2; negative cofactor 2 beta; negative cofactor 2-beta; Protein Dr1; similar to down-regulator of transcription 1; TATA-binding protein-associated phosphoprotein; wu:fj15f04; zgc:152914
Gene Symbols Dr1
Host Species Rabbit
Immunogen Recombinant protein (or fragment)).
Purification Method Affinity Chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 13486, 1810
Target Species Human, Mouse
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Liquid
Isotype IgG
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Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov
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