Promotional price valid on web orders only. Your contract pricing may differ. Interested in signing up for a dedicated account number?
Learn More
  1. Home
  2. Products
  3. Antibodies
  4. Primary Antibodies
  5. All Primary Antibodies
  6. PIPA592857

Invitrogen™ DR4 Polyclonal Antibody
GREENER_CHOICE

Catalog No. PIPA592857
Change view
Click to view available options
Quantity:
100 μL
1 product options available for selection
Product selection table with 1 available options. Use arrow keys to navigate and Enter or Space to select.
Catalog No. Quantity
PIPA592857 100 μL
Use arrow keys to navigate between rows. Press Enter or Space to select a product option. 1 options available.
1 options
Catalog No. PIPA592857 Supplier Invitrogen™ Supplier No. PA592857
Add to Cart
Add to Cart

Description

Rabbit Polyclonal Antibody

Immunogen sequence: GGDPKCMDRV CFWRLGLLRG PGAEDNAHNE ILSNADSLST FVSEQQMESQ EPADLTGVTV QSPGEAQCLL GPAEAEGSQR RRLLVPANGA DPTETLMLFF DKFANIVPFD SWDQLMRQLD LTKNEIDVVR AGTAGPGDAL YAMLMKWVNK TGRNASIHTL LDALERMEER HAREKIQDLL VDSGKFIYLE DGTGSAVSLE; Positive Samples: DU145; Cellular Location: Membrane, Single-pass type I membrane protein.

TRAIL-R1 (CD261, DR4) is a type I transmembrane protein, also called TRAIL receptor 1. The ligand for this DR4 death receptor has been identified and termed TRAIL, which is a member of the TNF family. DR4, as many other receptors (Fas, TNFR1, etc.), mediates apoptosis and NF kappaB activation in many cells and tissues. Apoptosis, a programmed cell death, is a operating process in normal cellular differentiation and development of multicellular organisms. Apoptosis is induced by coupled of certain cytokines (TNF family - TNF, Fas ligand) and their death domain containing receptors (TNFR1, Fas receptor).
TRUSTED_SUSTAINABILITY

Specifications

Antigen DR4
Applications ELISA, Western Blot
Classification Polyclonal
Concentration 1.47 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
Gene TNFRSF10A
Gene Accession No. O00220
Gene Alias APO2; CD261; cytotoxic TRAIL receptor; death receptor 4; DR4; MGC9365; sCD261; soluble CD261; soluble TRAIL; sTRAIL; TNF receptor superfamily member 10a; TNF-related apoptosis-inducing ligand receptor 1; TNFRSF10A; TRAIL R1; TRAIL receptor 1; TRAILR1; TRAIL-R1; TRAILR-1; tumor necrosis factor receptor superfamily member 10A; tumor necrosis factor receptor superfamily member 10a variant 2; tumor necrosis factor receptor superfamily, member 10a
Gene Symbols TNFRSF10A
Host Species Rabbit
Immunogen Recombinant fusion protein containing a sequence corresponding to amino acids 269-468 of human TNFRSF10A (NP_0038353).
Purification Method Affinity Chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 8797
Target Species Human
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Liquid
Isotype IgG
Show More Show Less
Product Title
Select an issue

By clicking Submit, you acknowledge that you may be contacted by Fisher Scientific in regards to the feedback you have provided in this form. We will not share your information for any other purposes. All contact information provided shall also be maintained in accordance with our Privacy Policy.