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Invitrogen™ DR6 Monoclonal Antibody (03)
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Catalog No. PIMA531265
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100 μL
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PIMA531265 100 μL
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Catalog No. PIMA531265 Supplier Invitrogen™ Supplier No. MA531265
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Description

Mouse Monoclonal Antibody

This product is preservative free. It is recommended to add sodium azide to avoid contamination (final concentration 0.05%-0.1%). This antibody has specificity for Human TNFRSF21/DR6.

DR6 is widely expressed in human tissues and cell lines. The ligand for DR6 has not been identified. Apoptosis is induced by certain cytokines including TNF and Fas ligand of the TNF family through their death domain containing receptors, TNF-R1 and Fas. Several novel death receptors including DR3, DR4, and DR5 were recently identified. A new death domain containing receptor in the TNFR family was cloned recently and termed DR6 for death receptor-6. Like TNF-R1, DR6 interacts with death domain containing adapter molecule TRADD. Overexpression of DR6 induces apoptosis and activates NF-kappa-B and JNK.
TRUSTED_SUSTAINABILITY

Specifications

Antigen DR6
Applications ELISA
Classification Monoclonal
Clone 03
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with no preservative
Gene TNFRSF21
Gene Accession No. O75509
Gene Alias AA959878; BM-018; CD358; Death receptor 6; Death receptor-6; DR6; MGC31965; R74815; sCD358; sDR6; soluble CD358; soluble DR6; TNF receptor superfamily member 21; TNFR-related death receptor 6; TNFR-related death receptor-6; Tnfrsf21; TR7; Tumor necrosis factor receptor superfamily member 21; tumor necrosis factor receptor superfamily, member 21; UNQ437/PRO868
Gene Symbols TNFRSF21
Host Species Mouse
Immunogen Recombinant Human TNFRSF21/DR6 Protein (Met1-Leu350).
Purification Method Protein A
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 27242
Target Species Human
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG1
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