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Invitrogen™ Draxin Polyclonal Antibody
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Catalog No. PIPA5143683
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100 μL
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PIPA5143683 100 μL
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Catalog No. PIPA5143683 Supplier Invitrogen™ Supplier No. PA5143683
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Description

Rabbit Polyclonal Antibody

The antibody detects a significant 50 kDa* protein corresponding to the molecular mass of draxin on SDS-PAGE immunoblots of rat PC12 cells, rat P1 brain, and chick E9 brain. The antibody also shows low expression of draxin in adult mouse brain.

Chemorepulsive axon guidance protein required for the development of spinal cord and forebrain commissures. Acts as a chemorepulsive guidance protein for commissural axons during development. Able to inhibit or repel neurite outgrowth from dorsal spinal cord. Inhibits the stabilization of cytosolic beta-catenin (CTNNB1) via its interaction with LRP6, thereby acting as an antagonist of Wnt signaling pathway.
TRUSTED_SUSTAINABILITY

Specifications

Antigen Draxin
Applications Western Blot, Immunocytochemistry
Classification Polyclonal
Concentration 0.5 mg/mL
Conjugate Unconjugated
Formulation PBS with 1mg/mL BSA, 50% glycerol and 0.05% sodium azide
Gene DRAXIN
Gene Accession No. Q6PAL1, Q8NBI3
Gene Alias 2610109H07Rik; AGPA3119; C1orf187; Dorsal inhibitory axon guidance protein; dorsal repulsive axon guidance protein; Draxin; FLJ34999; MGC117222; Neucrin; neural tissue-specific cysteine-rich protein; PSEC0258; UNQ3119; UNQ3119/PRO10268
Gene Symbols DRAXIN
Host Species Rabbit
Immunogen Draxin synthetic peptide (coupled to KLH) corresponding to amino acid residues in the C-terminal region of human draxin. This peptide sequence is highly conserved in rat, mouse, and chick draxin.
Purification Method Antigen affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 374946, 691317, 70433
Target Species Human, Mouse, Rat
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Liquid
Isotype IgG
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