Invitrogen™ Draxin Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA572708

Catalog No. PIPA572708

Description

Specificity: At least three isoforms of Neucrin are known to exist; this antibody will detect the two shorter isoforms. Neucrin antibody is predicted to not cross-react with RILP.

Chemorepulsive axon guidance protein required for the development of spinal cord and forebrain commissures. Acts as a chemorepulsive guidance protein for commissural axons during development. Able to inhibit or repel neurite outgrowth from dorsal spinal cord. Inhibits the stabilization of cytosolic beta-catenin (CTNNB1) via its interaction with LRP6, thereby acting as an antagonist of Wnt signaling pathway.

Specifications

• Antigen: Draxin
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: DRAXIN
• Gene Alias: 2610109H07Rik; AGPA3119; C1orf187; Dorsal inhibitory axon guidance protein; dorsal repulsive axon guidance protein; Draxin; FLJ34999; MGC117222; Neucrin; neural tissue-specific cysteine-rich protein; PSEC0258; UNQ3119; UNQ3119/PRO10268
• Host Species: Rabbit
• Purification Method: Antigen Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 374946, 691317, 70433
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: ELISA, Immunohistochemistry (Paraffin), Western Blot
• Concentration: 1 mg/mL
• Formulation: PBS with 0.02% sodium azide
• Gene Accession No.: Q6PAL1, Q8NBI3
• Gene Symbols: DRAXIN
• Immunogen: Neucrin antibody for a 17 amino acid synthetic peptide near the carboxy terminus of human Neucrin. The immunogen is within the last 50 amino acids of NEUCRIN.
• Quantity: 100 μg
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Rat
• Product Type: Antibody
• Isotype: IgG

Safety and Handling

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