Invitrogen™ Draxin Polyclonal Antibody

Sheep Polyclonal Antibody

Supplier:  Invitrogen™ PA547816

Catalog No. PIPA547816

Description

In direct ELISAs, approximately 50% cross-reactivity with recombinant human Draxin is observed. Reconstitute at 0.2 mg/mL in sterile PBS.

Chemorepulsive axon guidance protein required for the development of spinal cord and forebrain commissures. Acts as a chemorepulsive guidance protein for commissural axons during development. Able to inhibit or repel neurite outgrowth from dorsal spinal cord. Inhibits the stabilization of cytosolic beta-catenin (CTNNB1) via its interaction with LRP6, thereby acting as an antagonist of Wnt signaling pathway.

Specifications

• Antigen: Draxin
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: DRAXIN
• Gene Alias: 2610109H07Rik; AGPA3119; C1orf187; Dorsal inhibitory axon guidance protein; dorsal repulsive axon guidance protein; Draxin; FLJ34999; MGC117222; Neucrin; neural tissue-specific cysteine-rich protein; PSEC0258; UNQ3119; UNQ3119/PRO10268
• Host Species: Sheep
• Purification Method: Antigen Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 691317, 70433
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Form: Lyophilized

• Applications: Immunohistochemistry (Frozen), Western Blot
• Concentration: 0.2 mg/mL
• Formulation: PBS with 5% trehalose and No Preservative
• Gene Accession No.: Q6PAL1
• Gene Symbols: DRAXIN
• Immunogen: Mouse myeloma cell line NS0-derived recombinant mouse Draxin Gly26-Ile343.
• Quantity: 100 μg
• Primary or Secondary: Primary
• Target Species: Mouse, Rat
• Product Type: Antibody
• Isotype: IgG