Invitrogen™ DRD2 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA5115142

Catalog No. PIPA5115142

Description

Antibody detects endogenous levels of total DRD2.

The DRD2 Dopamine Receptor is involved in the neuromodulation of appetitive behaviors. DRD2 may be linked to alcoholism and other substance-use disorders. Mutations in DRD2 in mice lead to the suppression of reward behavior with morphine and to the reduction of spontaneous movements, a phenotype resembling Parkinsons disease. Three alternatively spliced isoforms have been identified. DRD2 has been reported to be expressed in various regions of the brain, as well as in aorta, artery, eye, and spinal cord. ESTs have been isolated from normal pituitary and in brain, colon, lung, pancreas, and skeletal muscle cancer libraries.

Specifications

• Antigen: DRD2
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: DRD2
• Gene Alias: D(2) dopamine receptor; D2 receptor; D2DR; D2R; Dopamine 2 receptor; Dopamine D2 receptor; dopamine receptor 2; dopamine receptor D2; dopamine receptor D2 isoform; Drd2; Drd-2; seven transmembrane helix receptor
• Host Species: Rabbit
• Purification Method: Affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 13489, 1813, 24318
• Content And Storage: -20°C
• Form: Liquid

• Applications: Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
• Concentration: 1 mg/mL
• Formulation: PBS with 50% glycerol and 0.02% sodium azide
• Gene Accession No.: P14416, P61168, P61169
• Gene Symbols: DRD2
• Immunogen: A synthesized peptide derived from human DRD2(Accession P14416), corresponding to amino acid residues L252-H302.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Rat
• Product Type: Antibody
• Isotype: IgG

Safety and Handling

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