Invitrogen™ DRD3 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA533482

Catalog No. PIPA533482

Description

Percent identity with other species by BLAST analysis: Human, Chimpanzee, Gibbon, Monkey, Marmoset, Mouse, Dog, Bat, Hamster, Panda, Horse, Pig (100%).

This gene encodes the D3 subtype of the five (D1-D5) dopamine receptors. The activity of the D3 subtype receptor is mediated by G proteins which inhibit adenylyl cyclase. This receptor is localized to the limbic areas of the brain, which are associated with cognitive, emotional, and endocrine functions. Genetic variation in this gene may be associated with susceptibility to hereditary essential tremor 1. Alternative splicing of this gene results in transcript variants encoding different isoforms, although some variants may be subject to nonsense-mediated decay (NMD).

Specifications

• Antigen: DRD3
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: DRD3
• Gene Alias: D(3) dopamine receptor; D3 receptor; D3DR; D3nf; D3R; Dopamine 3 receptor; Dopamine D3 receptor; dopamine receptor 3; dopamine receptor D3; dopaminergic receptor D3; Drd3; essential tremor 1; ETM1; FET1
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 100061160, 100513049, 100769070, 13490, 1814, 487984
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Immunohistochemistry (Paraffin)
• Concentration: 1 mg/mL
• Formulation: PBS with 0.1% sodium azide
• Gene Accession No.: P30728, P35462
• Gene Symbols: DRD3
• Immunogen: Synthetic 18 amino acid peptide from 3rd cytoplasmic domain of human DRD3 / Dopamine Receptor D3.
• Quantity: 50 μg
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Canine, Monkey, Hamster, Pig, Horse, Bat
• Product Type: Antibody
• Isotype: IgG

Safety and Handling

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