Invitrogen™ DRD3 Recombinant Rabbit Monoclonal Antibody (5L1P4)

Rabbit Recombinant Monoclonal Antibody

Supplier:  Invitrogen™ MA538119

Catalog No. PIMA538119

Description

Positive Samples: HeLa, C6, SH-SY5Y, U-251MG, Mouse brain Immunogen sequence: MASLSQLSGH LNYTCGAENS TGASQARPHA YYALSYCALI LAIVFGNGLV CMAVLKERAL QTTTNYLVVS LAVADLLVAT LVMPWVVYLE VTGGVWNFSR.

This gene encodes the D3 subtype of the five (D1-D5) dopamine receptors. The activity of the D3 subtype receptor is mediated by G proteins which inhibit adenylyl cyclase. This receptor is localized to the limbic areas of the brain, which are associated with cognitive, emotional, and endocrine functions. Genetic variation in this gene may be associated with susceptibility to hereditary essential tremor 1. Alternative splicing of this gene results in transcript variants encoding different isoforms, although some variants may be subject to nonsense-mediated decay (NMD).

Specifications

• Antigen: DRD3
• Classification: Recombinant Monoclonal
• Concentration: 0.33 mg/mL
• Formulation: PBS with 0.05% BSA, 50% glycerol and 0.02% sodium azide; pH 7.3
• Gene Accession No.: P19020, P30728, P35462
• Gene Symbols: DRD3
• Immunogen: A synthetic peptide corresponding to a sequence within amino acids 1-100 of human Dopamine Receptor D3 (DRD3) (P35462).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Rat
• Product Type: Antibody
• Isotype: IgG

• Applications: ELISA, Western Blot
• Clone: 5L1P4
• Conjugate: Unconjugated
• Gene: DRD3
• Gene Alias: D(3) dopamine receptor; D3 receptor; D3DR; D3nf; D3R; Dopamine 3 receptor; Dopamine D3 receptor; dopamine receptor 3; dopamine receptor D3; dopaminergic receptor D3; Drd3; essential tremor 1; ETM1; FET1
• Host Species: Rabbit
• Purification Method: Affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 13490, 1814, 29238
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Form: Liquid