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Invitrogen™ CRMP1 Recombinant Rabbit Monoclonal Antibody (JU73-30)
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Catalog No. PIMA534636
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100 μL
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PIMA534636 100 μL
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Catalog No. PIMA534636 Supplier Invitrogen™ Supplier No. MA534636
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Description

Rabbit Recombinant Monoclonal Antibody

Positive Control: Mouse brain tissue, N2A, SHG-44, SH-SY5Y, rat brain tissue, mouse cerebellum tissue.

Collapsin-response mediator proteins (CRMPs) are highly expressed in the developing brain where they play major roles in axonal outgrowth, neurite differentiation, and apoptosis. Their continued expression in areas of high synaptic remodeling such as the cerebellum, hippocampus, and the olfactory system suggests that these proteins may also be involved in adult brain plasticity. CRMP-1 was initially identified as a dihydro-pyrimidinase expressed exclusively in brain; later studies have shown that it is involved with neurotrophin (NT) 3-induced neurite formation and outgrowth. CRMP-1 localization switches from axonal to somatodendritic when neurons reach functional maturity, suggesting that it is involved in early neuronal differentiation as well as in later processes related to the survival or death of the newly generated neurons.
TRUSTED_SUSTAINABILITY

Specifications

Antigen CRMP1
Applications Flow Cytometry, Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
Classification Recombinant Monoclonal
Clone JU73-30
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation TBS with 0.05% BSA, 40% glycerol and 0.05% sodium azide; pH 7.4
Gene CRMP1
Gene Accession No. Q14194
Gene Alias Collapsin response mediator protein 1; Crmp1; CRMP-1; dihydropyrimidinase-like 1; dihydropyrimidinase-related protein 1; Dpysl1; DRP1; DRP-1; Ulip3; ULIP-3; Unc-33-like phosphoprotein 3
Gene Symbols CRMP1
Host Species Rabbit
Immunogen Synthetic peptide within Human CRMP1 aa 489-538.
Purification Method Protein A
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 1400
Target Species Human
Content And Storage -20°C, Avoid Freeze/Thaw Cycles, store in dark
Product Type Antibody
Form Liquid
Isotype IgG
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