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Tocris Bioscience™ DS2
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Catalog No. 367910R
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Catalog No. Quantity
36-791-0R 10 mg
36-795-0R 50 mg
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Catalog No. 36-791-0R Supplier Tocris Bioscience™ Supplier No. 3679/10
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Description

Positive allosteric modulator of δ-containing GABAA receptors

DS2 is a positive allosteric modulator of GABAA receptors. Potentiates GABA-evoked currents mediated by α4β3δ receptors (EC50 = 142 nM, in vitro). Displays complex selectivity profile, with selectivity for δ-containing receptors (α4/6βxδ > α1βxδ >> γ2 > α4β3 GABAA receptors). Enhances tonic currents of thalamocortical neurons in wild-type mice.

Specifications

Quantity 10 mg
Product Type DS2
Purity >97%
Molecular Weight (g/mol) 353.83
Inhibitors DS2

For Research Use Only

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