DSG3 Mouse anti-Human, Clone: 6G2C11, Abnova™
Mouse monoclonal antibody raised against partial recombinant human DSG3.
Manufacturer: Abnova Corporation MAB12254
Desmosomes are cell-cell junctions between epithelial, myocardial, and certain other cell types. Desmoglein 3 is a calcium-binding transmembrane glycoprotein component of desmosomes in vertebrate epithelial cells. Currently, three desmoglein subfamily members have been identified and all are members of the cadherin cell adhesion molecule superfamily. These desmoglein gene family members are located in a cluster on chromosome 18. This protein has been identified as the autoantigen of the autoimmune skin blistering disease pemphigus vulgaris. [provided by RefSeq]
|Mouse monoclonal antibody raised against partial recombinant human DSG3.|
|In PBS (0.05% sodium azide)|
|ELISA, Flow Cytometry, Immunohistochemistry (PFA fixed), Western Blot|
|ELISA (1:10000) Flow Cytometry (1:200-1:400) Immunohistochemistry (1:200-1:1000) Western Blot (1:500-1:2000) The optimal working dilution should be determined by the end user.|
|Recombinant protein corresponding to amino acids 55-159 of human DSG3.|
|Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.
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