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Invitrogen™ DSPG3 Monoclonal Antibody (340908)
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Catalog No. PIMA524074
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100 μg
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PIMA524074 100 μg
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Catalog No. PIMA524074 Supplier Invitrogen™ Supplier No. MA524074
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Description

Rat Monoclonal Antibody

In direct ELISAs and Western blots, approximately 50% cross-reactivity with recombinant human DSPG3 is observed. Reconstitute at 0.5 mg/mL in sterile PBS.

The DSPG3 gene is not well-characterized and does not appear in standard genomic databases as a distinct gene or protein coding entity. It is possible that DSPG3 refers to a specific type of dermatan sulfate proteoglycan, given the acronym DSPG, which typically relates to proteoglycans involved in extracellular matrix structure and modulation. Proteoglycans like dermatan sulfate proteoglycans are pivotal in maintaining tissue resilience and regulating cell signaling pathways by interacting with growth factors and cytokines. They contribute to developmental processes and tissue repair mechanisms, playing roles in cellular adhesion, proliferation, and migration. In the context of skeletal and connective tissues, DSPGs influence matrix assembly and modulate biomechanical properties, impacting processes such as angiogenesis and fibrosis. Proteoglycans are known for their importance in disease states, including cancer and fibrosis, where altered expression or structure can affect cellular interactions and disease progression. Further research is needed to understand the specifics of DSPG3's functions and its implications in health and disease.
TRUSTED_SUSTAINABILITY

Specifications

Antigen DSPG3
Applications Western Blot
Classification Monoclonal
Clone 340908
Concentration 0.5 mg/mL
Conjugate Unconjugated
Formulation PBS with 5% trehalose and No Preservative
Gene EPYC
Gene Accession No. P70186
Gene Alias Dermatan sulfate proteoglycan 3; dermatan sulphate proteoglycan 3; Dspg3; DSPG3proteoglycan-lb; Epiphycan; epiphycan proteoglycan; EPYC; Pglb; PG-Lb; Proteoglycan-Lb; SLRR3B; Small chondroitin/dermatan sulfate proteoglycan
Gene Symbols EPYC
Host Species Rat
Immunogen Mouse myeloma cell line NS0-derived recombinant mouse DSPG3 Ala20-Ile322.
Purification Method Protein A/G
Quantity 100 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 13516
Target Species Mouse
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Lyophilized
Isotype IgG2b
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