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Invitrogen™ DST Polyclonal Antibody
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Catalog No. PIPA576027
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100 μL
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PIPA576027 100 μL
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Catalog No. PIPA576027 Supplier Invitrogen™ Supplier No. PA576027
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Description

Rabbit Polyclonal Antibody

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

As basal cells of stratified squamous epithelia begin to migrate in response to wound healing, they lose their cell-substrate adhesion junctions, the hemidesmosomes. The hemidesmosome is an adhesion structure of the epidermal-dermal junction in keratinocytes. When keratinocytes migrate laterally or upward to differentiate they must control the formation and disintegration of the hemidesmosomes. The bullous pemphigoid antigen BPAG1 is a hemidesmosomal protein of the cutaneous basement membrane zone. The primary sequence deduced from full-length human cDNAs predicts that this molecule consists of a central rod region and flanking globular domains. A neuronal isoform, BPAG1n3 is the result of differential splicing of BPAG1. BPAG1n3 is distinguished by its initial 32 amino acid residues and by the absence of the amino-terminal half of the actin-binding domain.
TRUSTED_SUSTAINABILITY

Specifications

Antigen DST
Applications Immunohistochemistry (Paraffin), Western Blot
Classification Polyclonal
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.02% sodium azide; pH 7.2
Gene DST
Gene Accession No. Q03001, Q91ZU6
Gene Alias 230 kDa bullous pemphigoid antigen; 230/240 kDa bullous pemphigoid antigen; 2310001O04Rik; A830042E19Rik; ah; athetoid; AW554249; BP230; BP240; BPA; Bpag; Bpag1; BPAG1-n; bullous pemphigoid antigen 1; bullous pemphigoid antigen 1, isoform 5; bullous pemphigoid antigen 1, isoforms 1/2/3/4; bullous pemphigoid antigen 1, isoforms 6/7; CATX15; CATX-15; D6S1101; DMH; DST; DT; dystonia musculorum protein; Dystonin; EBSB2; Hemidesmosomal plaque protein; HSAN6; KIAA0728; MACF2; microtubule actin cross-linking factor 2; mKIAA0728; nmf203; nmf339; trabeculin-beta
Gene Symbols DST
Host Species Rabbit
Immunogen Recombinant full length Human DST.
Purification Method Antigen Affinity Chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 13518, 316313, 667
Target Species Human, Mouse, Rat
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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