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Invitrogen™ DST Polyclonal Antibody
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Catalog No. PIPA596034
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PIPA596034 100 μL
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Catalog No. PIPA596034 Supplier Invitrogen™ Supplier No. PA596034
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Description

Rabbit Polyclonal Antibody

Immunogen sequence: MHSSSYSYRS SDSVFSNTTS TRTSLDSNEN LLLVHCGPTL INSCISFGSE SFDGHRLEML QQIANRVQRD SVICEDKLIL AGNALQSDSK RLESGVQFQN EAEIAGYILE CENLLRQHVI DVQILIDGKY YQADQLVQRV AKLRDEIMAL RNECSSVYSK GRILTTEQTK LMISGITQSL NSGFAQTLHP SLTSGLTQSL TPSLTSSSMT SGLSSGMTSR LTPSVTPAYT PGFPSGLVPN FSSGVEPNSL QTLKLMQIRK PLLKSSLLDQ; Positive Samples: THP-1, Rat kidney; Cellular Location: Cell junction, Cell membrane, Cell projection, Cytoplasm, Endoplasmic reticulum membrane, H zone, Lipid-anchor, Membrane, Nucleus, Nucleus envelope, Single-pass membrane protein, Z line, axon, cell cortex, cytoskeleton, cytoskeleton, hemidesmosome, myofibril, sarcomere.

As basal cells of stratified squamous epithelia begin to migrate in response to wound healing, they lose their cell-substrate adhesion junctions, the hemidesmosomes. The hemidesmosome is an adhesion structure of the epidermal-dermal junction in keratinocytes. When keratinocytes migrate laterally or upward to differentiate they must control the formation and disintegration of the hemidesmosomes. The bullous pemphigoid antigen BPAG1 is a hemidesmosomal protein of the cutaneous basement membrane zone. The primary sequence deduced from full-length human cDNAs predicts that this molecule consists of a central rod region and flanking globular domains. A neuronal isoform, BPAG1n3 is the result of differential splicing of BPAG1. BPAG1n3 is distinguished by its initial 32 amino acid residues and by the absence of the amino-terminal half of the actin-binding domain.
TRUSTED_SUSTAINABILITY

Specifications

Antigen DST
Applications ELISA, Western Blot
Classification Polyclonal
Concentration 1.27 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.01% thimerosal; pH 7.3
Gene DST
Gene Accession No. Q03001, Q91ZU6
Gene Alias 230 kDa bullous pemphigoid antigen; 230/240 kDa bullous pemphigoid antigen; 2310001O04Rik; A830042E19Rik; ah; athetoid; AW554249; BP230; BP240; BPA; Bpag; Bpag1; BPAG1-n; bullous pemphigoid antigen 1; bullous pemphigoid antigen 1, isoform 5; bullous pemphigoid antigen 1, isoforms 1/2/3/4; bullous pemphigoid antigen 1, isoforms 6/7; CATX15; CATX-15; D6S1101; DMH; DST; DT; dystonia musculorum protein; Dystonin; EBSB2; Hemidesmosomal plaque protein; HSAN6; KIAA0728; MACF2; microtubule actin cross-linking factor 2; mKIAA0728; nmf203; nmf339; trabeculin-beta
Gene Symbols DST
Host Species Rabbit
Immunogen Recombinant fusion protein containing a sequence corresponding to amino acids 1-270 of human DST (NP_0017141).
Purification Method Affinity Chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 13518, 316313, 667
Target Species Human, Mouse, Rat
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Liquid
Isotype IgG
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Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov
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