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Invitrogen™ DST Polyclonal Antibody
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Catalog No. PIPA556396
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100 μL
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PIPA556396 100 μL
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Catalog No. PIPA556396 Supplier Invitrogen™ Supplier No. PA556396
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Description

Rabbit Polyclonal Antibody

Immunogen sequence: KPRCQNVAED MDIQLCASIL NENSDENENI NTMILLDKMH SCSSLEKQQR VNVVQLASPS ENNLVTEKSN LPEYTTEIAG KSKENLLNHE Highest antigen sequence identity to the following orthologs: Mouse - 33%, Rat - 33%.

As basal cells of stratified squamous epithelia begin to migrate in response to wound healing, they lose their cell-substrate adhesion junctions, the hemidesmosomes. The hemidesmosome is an adhesion structure of the epidermal-dermal junction in keratinocytes. When keratinocytes migrate laterally or upward to differentiate they must control the formation and disintegration of the hemidesmosomes. The bullous pemphigoid antigen BPAG1 is a hemidesmosomal protein of the cutaneous basement membrane zone. The primary sequence deduced from full-length human cDNAs predicts that this molecule consists of a central rod region and flanking globular domains. A neuronal isoform, BPAG1n3 is the result of differential splicing of BPAG1. BPAG1n3 is distinguished by its initial 32 amino acid residues and by the absence of the amino-terminal half of the actin-binding domain.
TRUSTED_SUSTAINABILITY

Specifications

Antigen DST
Applications Immunohistochemistry (Paraffin), Immunocytochemistry
Classification Polyclonal
Concentration 0.2 mg/mL
Conjugate Unconjugated
Formulation PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
Gene DST
Gene Accession No. Q03001
Gene Alias 230 kDa bullous pemphigoid antigen; 230/240 kDa bullous pemphigoid antigen; 2310001O04Rik; A830042E19Rik; ah; athetoid; AW554249; BP230; BP240; BPA; Bpag; Bpag1; BPAG1-n; bullous pemphigoid antigen 1; bullous pemphigoid antigen 1, isoform 5; bullous pemphigoid antigen 1, isoforms 1/2/3/4; bullous pemphigoid antigen 1, isoforms 6/7; CATX15; CATX-15; D6S1101; DMH; DST; DT; dystonia musculorum protein; Dystonin; EBSB2; Hemidesmosomal plaque protein; HSAN6; KIAA0728; MACF2; microtubule actin cross-linking factor 2; mKIAA0728; nmf203; nmf339; trabeculin-beta
Gene Symbols DST
Host Species Rabbit
Immunogen Recombinant protein corresponding to Human DST. Recombinant protein control fragment (Product #RP-94902).
Purification Method Antigen affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 667
Target Species Human
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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