DTD1 Monoclonal Antibody (OTI1E1), TrueMAB™, OriGene

Mouse Monoclonal Antibody

Supplier:  OriGene TA506880

Catalog No. 50-167-6827

Description

An aminoacyl-tRNA editing enzyme that deacylates mischarged D-aminoacyl-tRNAs. Also deacylates mischarged glycyl-tRNA(Ala), protecting cells against glycine mischarging by AlaRS. Acts via tRNA-based rather than protein-based catalysis; rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality. Possible ATPase involved in DNA replication, may facilitate loading of CDC45 onto pre-replication complexes.

Specifications

• Antigen: DTD1
• Classification: Monoclonal
• Concentration: 1 mg/mL
• Formulation: PBS with 1% BSA, 50% glycerol and 0.02% sodium azide
• Gene Accession No.: Q8TEA8
• Gene Symbols: DTD1
• Immunogen: Full length human recombit protein of human DTD1 produced in HEK293T cell.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG1

• Applications: Immunocytochemistry, Immunofluorescence, Western Blot
• Clone: OTI1E1
• Conjugate: Unconjugated
• Gene: DTD1
• Gene Alias: C20orf88, DTD, DUE-B, DUEB, HARS2, pqn-68
• Host Species: Mouse
• Purification Method: Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 92675
• Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
• Form: Liquid