Invitrogen™ DTNA Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA588329

Catalog No. PIPA588329

Description

Immunogen sequence: PVECSYCHSE SMMGFRYRCQ QCHNYQLCQD CFWRGHAGGS HSNQHQMKEY TSWKSPAKKL TNALSKSLSC ASSREPLHPM FPDQPEKPLN LAHIVDTWPP RPVTSMNDTL FSHSVPSSGS PFITRSSPPK DSEVEQNKLL ARAAPAFLKG KGIQYSLNVA DRLADEHVLI GLYVNMLRNN PSCMLESSNR LDEEHRLIAR YAARLAAESS SSQPPQQRSA PDISFTIDAN KQQRQLIAEL E; Positive Samples: U-87MG, Mouse brain; Cellular Location: Cell junction, Cell membrane, Cytoplasm, synapse.

The protein encoded by this gene belongs to the dystrobrevin subfamily of the dystrophin family. This protein is a component of the dystrophin-associated protein complex (DPC), which consists of dystrophin and several integral and peripheral membrane proteins, including dystroglycans, sarcoglycans, syntrophins and alpha- and beta-dystrobrevin. The DPC localizes to the sarcolemma and its disruption is associated with various forms of muscular dystrophy. Mutations in this gene are associated with left ventricular noncompaction with congenital heart defects. Multiple alternatively spliced transcript variants encoding different isoforms have been identified for this gene.

Specifications

• Antigen: DTNA
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: DTNA
• Gene Alias: 2210407P21Rik; a-DB-1; adbn; Alpha-dystrobrevin; D18S892E; DRP3; Dtn; Dtna; DTN-A; Dtna-ps1; dystrobrevin alpha; dystrobrevin alpha, pseudogene 1; dystrobrevin, alpha; dystrophin-related protein 3; Gm19389; LVNC1; RGD1561985
• Host Species: Rabbit
• Purification Method: Affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 13527, 1837
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Form: Liquid

• Applications: ELISA, Western Blot
• Concentration: 0.03 mg/mL
• Formulation: PBS with 50% glycerol and 0.01% thimerosal; pH 7.3
• Gene Accession No.: Q9D2N4, Q9Y4J8
• Gene Symbols: DTNA
• Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 240-480 of human DTNA (NP_0013812).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse
• Product Type: Antibody
• Isotype: IgG

Safety and Handling

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