Invitrogen™ DTNBP1 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA5119711

Catalog No. PIPA5119711

Description

Positive Control: Daudi cell lysate, MCF-7 cell lysate, HL-60 cell lysate, human spleen tissue, mouse testis tissue, MCF-7. Subcellular Location: Cell junction, Cell membrane, Cytoplasm, Cytoplasmic vesicle, Endoplasmic reticulum, Endosome, Membrane, Nucleus, Postsynaptic cell membrane, Synapse.

Dtnbp1 may play a role in organelle biogenesis associated with melanosomes, platelet dense granules, and lysosomes. A similar protein in mouse is a component of a protein complex termed biogenesis of lysosome-related organelles complex 1 (BLOC-1), and binds to alpha- and beta-dystrobrevins, which are components of the dystrophin-associated protein complex (DPC). Mutations are associated with Hermansky-Pudlak syndrome type 7. This protein may also be associated with schizophrenia.

Specifications

• Antigen: DTNBP1
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: DTNBP1
• Gene Alias: 5430437B18Rik; AW048963; biogenesis of lysosomal organelles complex-1, subunit 8; biogenesis of lysosome-related organelles complex 1 subunit 8; BLOC-1 subunit 8; Bloc1s8; DBND; distrobrevin binding protein 1; DKFZp564K192; DTBP1; Dtnbp1; Dysbindin; dysbindin-1; dystrobrevin binding protein 1; dystrobrevin-binding protein 1; FLJ30031; Hermansky-Pudlak syndrome 7 protein; hermansky-Pudlak syndrome 7 protein homolog; HPS7; HPS7 protein; HPS7 protein homolog; Hps7-like protein; MGC20210; My031; OTTHUMP00000221462; OTTHUMP00000221485; RP1-147M19.1; sandy; sdy
• Host Species: Rabbit
• Purification Method: Antigen Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 84062, 94245
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Flow Cytometry, Immunohistochemistry (Paraffin), Western Blot
• Concentration: 1 mg/mL
• Formulation: TBS with 50% glycerol and 0.05% sodium azide; pH 7.4
• Gene Accession No.: Q91WZ8, Q96EV8
• Gene Symbols: DTNBP1
• Immunogen: Recombinant protein within human Dysbindin aa 150-351.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse
• Product Type: Antibody
• Isotype: IgG