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Tocris Bioscience™ dTRIM 24

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Quantity:
5 mg
Description
Degrader (PROTAC®) composed of the TRIM24 ligand IACS-9571 conjugated to a VHL ligand. Displays dose- and time-dependent degradation of TRIM24 in cells, with maximum degradation achieved at 5 μM. Degradation phenotypically mirrors genetic deletion of TRIM24. Demonstrates antiproliferative effects in MOLM-13 cells. Cell permeable.
PROTAC® is a registered trademark of Arvinas Operations, Inc., and is used under license.
Specifications
Specifications
CAS | 2170695-14-2 |
Quantity | 5 mg |
Molecular Formula | C55H68N8O13S2 |
Formula Weight | 1113.3 |
Product Type | Degrader |
Purity | 98% |
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