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DTX2 Rabbit anti-Human, Mouse, Rat, Polyclonal, Proteintech
SDP

Catalog No. 501732179 Shop All Proteintech Group Inc Products
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50-173-2179 150 μL
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Catalog No. 50-173-2179 Supplier Proteintech Group Inc Supplier No. 185651AP150UL
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Rabbit Polyclonal Antibody

DTX2 functions as an E3 ubiquitin ligase. Regulator of Notch signaling, a signaling pathway involved in cell-cell communications that regulates a broad spectrum of cell-fate determinations. Probably acts both as a positive and negative regulator of Notch, depending on the developmental and cell context. Mediates the antineural activity of Notch, possibly by inhibiting the transcriptional activation mediated by MATCH1. Functions as an ubiquitin ligase protein in vitro, suggesting that it may regulate the Notch pathway via some ubiquitin ligase activity.

Specifications

Antigen DTX2
Applications Immunohistochemistry (Paraffin)
Classification Polyclonal
Concentration 0.19 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
Gene DTX2
Gene Accession No. Q86UW9, Q8R3P2
Gene Alias deltex homolog 2 (Drosophila), Deltex2, DTX2, hDTX2, KIAA1528, Protein deltex 2, RING finger protein 58, RNF58
Gene Symbols Dtx2
Host Species Rabbit
Immunogen DTX2 Fusion Protein Ag4376
Purification Method Antigen Affinity Chromatography
Quantity 150 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 113878, 304591, 74198
Target Species Human, Mouse, Rat
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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