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Invitrogen™ DTX3L Polyclonal Antibody
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Catalog No. PIPA530691
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100 μL
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PIPA530691 100 μL
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Catalog No. PIPA530691 Supplier Invitrogen™ Supplier No. PA530691
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Description

Rabbit Polyclonal Antibody

Recommended positive controls: 293T, A431, Jurkat. Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.

Component of the shelterin complex (telosome) that is involved in the regulation of telomere length and protection. Shelterin associates with arrays of double-stranded TTAGGG repeats added by telomerase and protects chromosome ends. Without its protective activity, telomeres are no longer hidden from the DNA damage surveillance and chromosome ends are inappropriately processed by DNA repair pathways. Promotes binding of POT1 to single-stranded telomeric DNA. Modulates the inhibitory effects of POT1 on telomere elongation. The ACD-POT1 heterodimer enhances telomere elongation by recruiting telomerase to telomeres and increasing its processivity. May play a role in organogenesis.
TRUSTED_SUSTAINABILITY

Specifications

Antigen DTX3L
Applications Western Blot
Classification Polyclonal
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 1% BSA, 20% glycerol and 0.01% thimerosal; pH 7
Gene DTX3L
Gene Accession No. Q8TDB6
Gene Alias AU042200; Bbap; BC023741; B-lymphoma- and BAL-associated protein; deltex 3 like, E3 ubiquitin ligase; deltex 3-like; deltex 3-like (Drosophila); deltex E3 ubiquitin ligase 3L; DTX3L; E3 ubiquitin-protein ligase DTX3L; Protein deltex-3-like; RGD1565144; rhysin 2; Rhysin2; rhysin-2; RING-type E3 ubiquitin transferase DTX3L
Gene Symbols DTX3L
Host Species Rabbit
Immunogen Recombinant protein encompassing a sequence within the N-terminus region of human DTX3L. The exact sequence is proprietary.
Purification Method Antigen affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 151636
Target Species Human
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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