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DTX3L Rabbit anti-Human, Polyclonal, Bioss
SDP

Catalog No. 501983272
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50-198-3272 100 μL
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Catalog No. 50-198-3272 Supplier Bioss Supplier No. BS14438R
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Description

Rabbit Polyclonal Antibody

Component of the shelterin complex (telosome) that is involved in the regulation of telomere length and protection. Shelterin associates with arrays of double-stranded TTAGGG repeats added by telomerase and protects chromosome ends. Without its protective activity, telomeres are no longer hidden from the DNA damage surveillance and chromosome ends are inappropriately processed by DNA repair pathways. Promotes binding of POT1 to single-stranded telomeric DNA. Modulates the inhibitory effects of POT1 on telomere elongation. The ACD-POT1 heterodimer enhances telomere elongation by recruiting telomerase to telomeres and increasing its processivity. May play a role in organogenesis.

Specifications

Antigen DTX3L
Applications Immunohistochemistry (Paraffin), Western Blot
Classification Polyclonal
Concentration 1 μg/mL
Conjugate Unconjugated
Formulation PBS with 1% BSA, 50% glycerol and 0.09% sodium azide; pH
Gene DTX3L
Gene Accession No. Q8TDB6
Gene Alias BBAP; B-lymphoma- and BAL-associated protein; deltex 3 like, E3 ubiquitin ligase; deltex 3-like; deltex E3 ubiquitin ligase 3L; DTX3L; E3 ubiquitin-protein ligase DTX3L; Protein deltex-3-like; rhysin 2; Rhysin2; Rhysin-2; RING-type E3 ubiquitin transferase DTX3L
Gene Symbols DTX3L
Host Species Rabbit
Immunogen KLH conjugated synthetic peptide derived from human DTX3L.
Purification Method Protein A
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 151636
Target Species Human
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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