DTX3L Rabbit anti-Human, Polyclonal, Proteintech

Rabbit Polyclonal Antibody

Catalog Number	Mfr. No.	Quantity
50-172-7599	Proteintech Group Inc 119631AP150UL	150 μL

Description

Component of the shelterin complex (telosome) that is involved in the regulation of telomere length and protection. Shelterin associates with arrays of double-stranded TTAGGG repeats added by telomerase and protects chromosome ends. Without its protective activity, telomeres are no longer hidden from the DNA damage surveillance and chromosome ends are inappropriately processed by DNA repair pathways. Promotes binding of POT1 to single-stranded telomeric DNA. Modulates the inhibitory effects of POT1 on telomere elongation. The ACD-POT1 heterodimer enhances telomere elongation by recruiting telomerase to telomeres and increasing its processivity. May play a role in organogenesis.

Specifications

• Antigen: DTX3L
• Applications: Western Blot
• Conjugate: Unconjugated
• Host Species: Rabbit
• Target Species: Human
• Gene Accession No.: Q8TDB6
• Gene ID (Entrez): 151636
• Immunogen: DTX3L Fusion Protein Ag2568
• Primary or Secondary: Primary
• Content And Storage: -20°C
• Gene: DTX3L

• Concentration: 0.33 mg/mL
• Classification: Polyclonal
• Form: Liquid
• Regulatory Status: RUO
• Formulation: PBS with 50% glycerol and 0.1% sodium azide; pH 7.3
• Gene Alias: BBAP, deltex 3 like (Drosophila), DTX3L, Protein deltex 3 like, Rhysin 2, Rhysin2
• Gene Symbols: DTX3L
• Isotype: IgG
• Purification Method: Antigen Affinity Chromatography
• Product Type: Antibody