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Invitrogen™ DTYMK Monoclonal Antibody (C17), Invitrogen™

Catalog No. FEMA550988
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200 μL
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FEMA550988 20 μL
FEMA550987 200 μL
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Catalog No. FEMA550988 Supplier Invitrogen™ Supplier No. MA550988
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Description

Mouse Monoclonal Antibody

Thymidylate kinase (DTYMK) catalyzes the phosphorylation of dTMP to form dTDP in the dTTP synthesis pathway for DNA synthesis. DTYMK is essential for DNA synthesis and is an important intermediate enzyme in the pathway of many pyrimidine analog drugs, including 5-Fluorouracil (5-FU), the chemotherapeutic drug of choice for several solid tumors. The human DTYMK gene was isolated via functional complementation of a Saccharomyces cerevisiae cell cycle mutant, cdc8. DTYMK mRNA levels and enzyme activities are regulated at the level of cell cycle and cell growth pathways.
TRUSTED_SUSTAINABILITY

Specifications

Antigen DTYMK
Applications Western Blot
Classification Monoclonal
Clone C17
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.05% Proclin 300; pH 7.4
Gene DTYMK
Gene Accession No. P97930
Gene Alias AU044245; CDC8; D10Ertd203e; deoxythymidylate kinase; deoxythymidylate kinase (thymidylate kinase); dTMP kinase; DTYMK; mtmk; PP3731; Thymidylate kinase; Tmk; TMPK; TYMK; TYPK
Gene Symbols DTYMK
Host Species Mouse
Immunogen Recombinant Mouse DTYMK protein, Pro43-Glu190 (Accession #P97930).
Purification Method Protein A/G
Quantity 20 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 21915, 301622
Target Species Mouse, Rat
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG1 κ
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