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DTYMK Monoclonal Antibody (OTI1D2), TrueMAB™, OriGene
SDP

Catalog No. 501674377
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30 μL
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50-167-4377 100 μL
50-254-0875 30 μL
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Catalog No. 50-167-4377 Supplier OriGene Supplier No. TA503497
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Mouse Monoclonal Antibody

Thymidylate kinase (DTYMK) catalyzes the phosphorylation of dTMP to form dTDP in the dTTP synthesis pathway for DNA synthesis. DTYMK is essential for DNA synthesis and is an important intermediate enzyme in the pathway of many pyrimidine analog drugs, including 5-Fluorouracil (5-FU), the chemotherapeutic drug of choice for several solid tumors. The human DTYMK gene was isolated via functional complementation of a Saccharomyces cerevisiae cell cycle mutant, cdc8. DTYMK mRNA levels and enzyme activities are regulated at the level of cell cycle and cell growth pathways.

Specifications

Antigen DTYMK
Applications Immunocytochemistry, Immunofluorescence, Western Blot
Classification Monoclonal
Clone OTI1D2
Concentration 0.76 mg/mL
Conjugate Unconjugated
Formulation PBS with 1% BSA, 50% glycerol and 0.02% sodium azide
Gene DTYMK
Gene Accession No. P23919
Gene Alias CDC8, PP3731, TMPK, TYMK
Gene Symbols DTYMK
Host Species Mouse
Immunogen Full length human recombit protein of human DTYMK produced in HEK293T cell.
Purification Method Affinity Chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 1841
Target Species Human
Content And Storage -20° C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Liquid
Isotype IgG1
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