Invitrogen™ DTYMK Monoclonal Antibody (OTI1G8)

Mouse Monoclonal Antibody

Supplier:  Invitrogen™ MA525678

Catalog No. PIMA525678

Description

DTYMK Monoclonal Antibody for Western Blot, ICC/IF, IHC (P), Flow

Thymidylate kinase (DTYMK) catalyzes the phosphorylation of dTMP to form dTDP in the dTTP synthesis pathway for DNA synthesis. DTYMK is essential for DNA synthesis and is an important intermediate enzyme in the pathway of many pyrimidine analog drugs, including 5-Fluorouracil (5-FU), the chemotherapeutic drug of choice for several solid tumors. The human DTYMK gene was isolated via functional complementation of a Saccharomyces cerevisiae cell cycle mutant, cdc8. DTYMK mRNA levels and enzyme activities are regulated at the level of cell cycle and cell growth pathways.

Specifications

• Antigen: DTYMK
• Classification: Monoclonal
• Concentration: 1 mg/mL
• Formulation: PBS with 1% BSA, 50% glycerol and 0.02% sodium azide; pH 7.3
• Gene Accession No.: P23919
• Gene Symbols: DTYMK
• Immunogen: Full length human recombinant protein of DTYMK produced in HEK293T cell.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG1

• Applications: Flow Cytometry, Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
• Clone: OTI1G8
• Conjugate: Unconjugated
• Gene: DTYMK
• Gene Alias: AU044245; CDC8; D10Ertd203e; deoxythymidylate kinase; deoxythymidylate kinase (thymidylate kinase); dTMP kinase; DTYMK; mtmk; PP3731; Thymidylate kinase; Tmk; TMPK; TYMK; TYPK
• Host Species: Mouse
• Purification Method: Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 1841
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Form: Liquid