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Invitrogen™ DTYMK Recombinant Rabbit Monoclonal Antibody (JE64-08)
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Catalog No. FEMA550665
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100 μL
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FEMA550665 100 μL
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Catalog No. FEMA550665 Supplier Invitrogen™ Supplier No. MA550665
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Description

Rabbit Recombinant Monoclonal Antibody

Positive control: K562 cell lysate, HepG2 cell lysate, NCI-H441, human kidney tissue. Predicted band size: 24 kDa Subcellular Location: Cytosol, mitochondrial intermembrane space, mitochondrial matrix, mitochondrion, nucleus, cytoplasm.

Thymidylate kinase (DTYMK) catalyzes the phosphorylation of dTMP to form dTDP in the dTTP synthesis pathway for DNA synthesis. DTYMK is essential for DNA synthesis and is an important intermediate enzyme in the pathway of many pyrimidine analog drugs, including 5-Fluorouracil (5-FU), the chemotherapeutic drug of choice for several solid tumors. The human DTYMK gene was isolated via functional complementation of a Saccharomyces cerevisiae cell cycle mutant, cdc8. DTYMK mRNA levels and enzyme activities are regulated at the level of cell cycle and cell growth pathways.
TRUSTED_SUSTAINABILITY

Specifications

Antigen DTYMK
Applications Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
Classification Recombinant Monoclonal
Clone JE64-08
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation TBS with 0.05% BSA, 40% glycerol and 0.05% sodium azide; pH 7.4
Gene DTYMK
Gene Accession No. P23919
Gene Alias AU044245; CDC8; D10Ertd203e; deoxythymidylate kinase; deoxythymidylate kinase (thymidylate kinase); dTMP kinase; DTYMK; mtmk; PP3731; Thymidylate kinase; Tmk; TMPK; TYMK; TYPK
Gene Symbols DTYMK
Host Species Rabbit
Immunogen Synthetic peptide within Human DTYMK aa 150-200/212.
Purification Method Protein A
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 1841
Target Species Human
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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