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DUBA Polyclonal Antibody, Bethyl Laboratories

Catalog No. 501563817
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Catalog No. Quantity
50-156-3817 20 μL
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Catalog No. 50-156-3817 Supplier Bethyl Laboratories, Inc Supplier No. A302920AT
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Description

Rabbit Polyclonal Antibody

The recommended shelf life for this product is 1 year from date of receipt. Based on 100% sequence identity, this antibody is predicted to react with Rat

This gene encodes a member of the OTU (ovarian tumor) domain-containing cysteine protease superfamily. The OTU domain confers deubiquitinase activity and the encoded protein has been shown to suppress the type I interferon-dependent innate immune response by cleaving the polyubiquitin chain from an essential type I interferon adaptor protein. Cleavage results in disassociation of the adaptor protein from a downstream signaling complex and disruption of the type I interferon signaling cascade. Alternatively spliced transcript variants encoding different isoforms have been described.

Specifications

Antigen DUBA
Applications Western Blot
Classification Polyclonal
Conjugate Unconjugated
Formulation TBS with 0.1% BSA and 0.09% sodium azide
Gene OTUD5
Gene Accession No. Q3U2S4, Q96G74
Gene Alias DUBA; OTU domain-containing protein 5; deubiquinating enzyme A; deubiquitinating enzyme A
Gene Symbols OTUD5
Host Species Rabbit
Immunogen Between 521 and 571
Purification Method Antigen affinity chromatography
Quantity 20 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 54644, 55593
Target Species Human, Mouse
Content And Storage 4° C
Product Type Antibody
Form Liquid
Isotype IgG
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