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Invitrogen™ DUSP11 Polyclonal Antibody
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Catalog No. PA551153
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100 μL
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PA551153 100 μL
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Catalog No. PA551153 Supplier Invitrogen™ Supplier No. PA551153
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Description

Rabbit Polyclonal Antibody

The antibody detects endogenous levels of total DUSP11 protein.

DUSP11 (dual specificity phosphatase 11 (RNA/RNP complex 1-interacting)) is a member of the dual specificity protein phosphatase subfamily. These phosphatases inactivate their target kinases by dephosphorylating both the phosphoserine/threonine and phosphotyrosine residues. They negatively regulate members of the mitogen-activated protein (MAP) kinase superfamily (MAPK/ERK, SAPK/JNK, p38), which is associated with cellular proliferation and differentiation. Different members of the family of dual specificity phosphatases show distinct substrate specificities for various MAP kinases, different tissue distribution and subcellular localization, and different modes of inducibility of their expression by extracellular stimuli. This gene product is localized to the nucleus, and is novel in that it binds directly to RNA and splicing factors, and thus suggested to participate in nuclear mRNA metabolism.
TRUSTED_SUSTAINABILITY

Specifications

Antigen DUSP11
Applications Immunohistochemistry (Paraffin)
Classification Polyclonal
Concentration 1.3 mg/mL
Conjugate Unconjugated
Formulation PBS with 40% glycerol and 0.05% sodium azide; pH 7.4
Gene DUSP11
Gene Accession No. O75319
Gene Alias 2010300F21Rik; AI481497; dual specificity phosphatase 11; dual specificity phosphatase 11 (RNA/RNP complex 1-interacting); dual specificity protein phosphatase 11; DUSP11; Phosphatase that interacts with RNA/RNP complex 1; PIR1; RNA/RNP complex 1-interacting; RNA/RNP complex-1-interacting phosphatase; RNA/RNP complex-1-interacting phosphatase-like protein; RNA/RNP complex-interacting phosphatase; serine/threonine specific protein phosphatase
Gene Symbols DUSP11
Host Species Rabbit
Immunogen Full length fusion protein of human DUSP11.
Purification Method Antigen affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 8446
Target Species Human
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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