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Invitrogen™ DUSP11 Polyclonal Antibody
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Catalog No. PIPA569080
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100 μL
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PIPA569080 100 μL
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Catalog No. PIPA569080 Supplier Invitrogen™ Supplier No. PA569080
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Description

Rabbit Polyclonal Antibody

This target displays homology in the following species: Cow: 86%; Dog: 86%; Horse: 79%; Human: 100%; Mouse: 79%; Pig: 86%; Rabbit: 86%; Rat: 79%.

DUSP11 (dual specificity phosphatase 11 (RNA/RNP complex 1-interacting)) is a member of the dual specificity protein phosphatase subfamily. These phosphatases inactivate their target kinases by dephosphorylating both the phosphoserine/threonine and phosphotyrosine residues. They negatively regulate members of the mitogen-activated protein (MAP) kinase superfamily (MAPK/ERK, SAPK/JNK, p38), which is associated with cellular proliferation and differentiation. Different members of the family of dual specificity phosphatases show distinct substrate specificities for various MAP kinases, different tissue distribution and subcellular localization, and different modes of inducibility of their expression by extracellular stimuli. This gene product is localized to the nucleus, and is novel in that it binds directly to RNA and splicing factors, and thus suggested to participate in nuclear mRNA metabolism.
TRUSTED_SUSTAINABILITY

Specifications

Antigen DUSP11
Applications Western Blot
Classification Polyclonal
Concentration 0.5 mg/mL
Conjugate Unconjugated
Formulation PBS with 2% sucrose and 0.09% sodium azide
Gene DUSP11
Gene Accession No. Q6NXK5
Gene Alias 2010300F21Rik; AI481497; dual specificity phosphatase 11; dual specificity phosphatase 11 (RNA/RNP complex 1-interacting); dual specificity protein phosphatase 11; DUSP11; Phosphatase that interacts with RNA/RNP complex 1; PIR1; RNA/RNP complex 1-interacting; RNA/RNP complex-1-interacting phosphatase; RNA/RNP complex-1-interacting phosphatase-like protein; RNA/RNP complex-interacting phosphatase; serine/threonine specific protein phosphatase
Gene Symbols DUSP11
Host Species Rabbit
Immunogen synthetic peptide directed towards the middle region of mouse DUSP11.
Purification Method Affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 72102
Target Species Mouse
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Liquid
Isotype IgG
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