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DUSP11 Rabbit anti-Human, Polyclonal, Proteintech
SDP

Catalog No. 50555645 Shop All Proteintech Group Inc Products
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50-555-645 150 μL
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Catalog No. 50-555-645 Supplier Proteintech Group Inc Supplier No. 102042AP150UL
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Description

Rabbit Polyclonal Antibody

DUSP11 (dual specificity phosphatase 11 (RNA/RNP complex 1-interacting)) is a member of the dual specificity protein phosphatase subfamily. These phosphatases inactivate their target kinases by dephosphorylating both the phosphoserine/threonine and phosphotyrosine residues. They negatively regulate members of the mitogen-activated protein (MAP) kinase superfamily (MAPK/ERK, SAPK/JNK, p38), which is associated with cellular proliferation and differentiation. Different members of the family of dual specificity phosphatases show distinct substrate specificities for various MAP kinases, different tissue distribution and subcellular localization, and different modes of inducibility of their expression by extracellular stimuli. This gene product is localized to the nucleus, and is novel in that it binds directly to RNA and splicing factors, and thus suggested to participate in nuclear mRNA metabolism.

Specifications

Antigen DUSP11
Applications Immunocytochemistry, Immunofluorescence, Western Blot
Classification Polyclonal
Concentration 0.4 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.1% sodium azide; pH 7.3
Gene DUSP11
Gene Accession No. O75319
Gene Alias DUSP11, PIR1
Gene Symbols DUSP11
Host Species Rabbit
Immunogen DUSP11 Fusion Protein Ag0276
Purification Method Antigen Affinity Chromatography
Quantity 150 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 8446
Target Species Human
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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