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Invitrogen™ DUSP12 Polyclonal Antibody
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Catalog No. PIPA530438
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100 μL
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PIPA530438 100 μL
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Catalog No. PIPA530438 Supplier Invitrogen™ Supplier No. PA530438
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Description

Rabbit Polyclonal Antibody

Recommended positive controls: A549, HeLa. Predicted reactivity: Mouse (87%), Rat (88%). Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.

Dual specificity phosphatase (DUSP) inactivate their target kinases by dephosphorylating both the phosphoserine/threonine and phosphotyrosine residues. DUSPs can be divided into six subgroups on the basis of sequence similarity (PRLs, Cdc14 phosphatases, PTENs, myotubularins, MKPs, atypical DUSPs). DUSP inhibitors might be used to manipulate MAPK and cellular responses in both positive and negative ways. The regulated expression and activity of DUSP family members in different cells and tissues controls MAPK intensity and duration to determine the type of physiological response. DUSP12 (YVH1, GKAP) contains the consensus DUSP catalytic domain as well as an extended C-terminal domain of unknown function, thought to be related to its potential role in glucokinase regulation. It is localized in the cytoplasm and nucleus.
TRUSTED_SUSTAINABILITY

Specifications

Antigen DUSP12
Applications Western Blot
Classification Polyclonal
Concentration 0.94 mg/mL
Conjugate Unconjugated
Formulation 0.1M tris glycine with 20% glycerol and 0.01% thimerosal; pH 7
Gene Dusp12
Gene Accession No. Q9UNI6
Gene Alias 1190004O14Rik; AA027408; AW049275; dual specificity phosphatase 12; dual specificity phosphatase T-DSP4; Dual specificity phosphatase VH1; dual specificity protein phosphatase 12; Dual specificity tyrosine phosphatase YVH1; DUSP1; Dusp12; ESTM36; LMW-DSP4; mVH1; serine/threonine specific protein phosphatase; T-DSP4; VH1; YVH1; YVH1 protein-tyrosine phosphatase ortholog
Gene Symbols Dusp12
Host Species Rabbit
Immunogen Recombinant protein encompassing a sequence within the center region of human DUSP12. The exact sequence is proprietary.
Purification Method Antigen affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 11266
Target Species Human
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov
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